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List of 1 Dengue Fever Medications Compared - Drugs.com

Details: Dengue fever is spread by the female Aedes mosquito that has been infected with dengue fever virus, of which there are five strains. As many as 80% of people infected with dengue virus have no symptoms or mild fever whereas others develop more severe symptoms of dengue fever. dengue fever treatment and prevention

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List of drugs/medicine used for Dengue / Dengue

Details: List of drugs used to treat the medical condition called Dengue / Dengue Hemorrhagic Fever. Click on the drug to find more information including the brand names,dose,side-effects, adverse events dengue fever symptom

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Which medications are used for the treatment of dengue?

Details: The treatment of dengue fever is symptomatic and supportive in nature. Bed rest and mild analgesic-antipyretic therapy are often helpful in relieving lethargy, malaise, and fever associated with dengue hemorrhagic fever treatment

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Recent update on anti-dengue drug discovery

Details: Dengue is the most important arthropod-borne viral disease of humans, with more than half of the global population living in at-risk areas. Despite the negative impact on public health, there are no antiviral therapies available, and the only licensed vaccine, Dengvaxia ®, has been contraindicated in children below nine years of age.In an effort to combat dengue, several small molecules have dengue treatment protocol

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Potent Dengue Antiviral Effective against All Known Variants

Details: The antiviral drug will be developed in an easy-to-administer formulation that can be optimized for the treatment and prevention of the disease in dengue … medicash dengue treatment

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Treatment Dengue CDC

Details: No treatment: No specific antiviral agents exist for dengue. Supportive care is advised: Patients should be advised to stay well hydrated and to avoid aspirin (acetylsalicylic acid), aspirin-containing drugs, and other nonsteroidal anti-inflammatory drugs (such as ibuprofen) because of their anticoagulant properties. Fever should be controlled with acetaminophen and tepid sponge baths. dengue hemorrhagic fever

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First Drug For Dengue, An Excruciating Disease, May Be On

Details: First drug for dengue, an excruciating disease, may be on the horizon. Deneen Broadnax 2 mins ago. 3 minutes read. Relief may be in sight for tropical hospitals that are increasingly overwhelmed during outbreaks of dengue, a viral disease that can cause excruciating pain and even death. A new study has identified a compound that blocks dengue signs and symptoms of dengue

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Dengue structural proteins as antiviral drug targets

Details: In this review, the possible drug targets for discovery and development of potential antiviral drugs against structural proteins of dengue virus, the current development status of the antiviral drugs against dengue around the world, and challenges that need to be addressed to overcome the shortcomings in the process of drug discovery have been

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Dengue Drugs Market by Distribution Channel, Type, Drug

Details: These research studies focused on using dengue drugs for the treatment of COVID-19 patients are propelling the growth of dengue drugs market across the globe. Drug Class Outlook: The acetaminophen drug class dominates the global dengue drugs market. In the early stages of dengue fever patients are given acetaminophen for alleviating fever or pain.

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World’s 1st dengue drug, made by Pinoys

Details: Besides the anti-dengue drug being developed by Pharmalytics and De La Salle, a herbal supplement against dengue was developed by Herbanext Laboratories. Herbanext’s herbal supplement from tawa-tawa, under the Daily Apple brand name, was released in August at the height of the dengue epidemic in the country.

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A step towards therapeutics for dengue

Details: An effective drug against dengue virus (DENV) is urgently needed, because this mosquito-transmitted virus represents a tremendous public-health burden, with …

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Symptoms and Treatment Dengue CDC

Details: Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. Severe dengue. About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and even death. If you have had dengue in the past, you are more likely to develop severe dengue.

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Dengue Drug Target Database - Bioinformatics

Details: DengueDT-DB is an effort to collect information about the dengue virus, dengue virus genes, dengue virus drugs targets and drugs, disease into a central portal to facilitate dengue researchers from several disciplines such as drug discovery, vaccine development, epidemiology and comparative genomics.

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Very potent antiviral against dengue: The antiviral is

Details: The antiviral drug will be developed in an easy-to-administer formulation that can be optimised for the treatment and prevention of the disease in dengue

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Ten years of dengue drug discovery: Progress and prospects

Details: The following sections review key dengue drug discovery progress made at the NITD, as well as major discoveries made by academia and other companies in the past ten years. 6. Entry inhibitors. Inhibiting viral entry is a proven antiviral approach, as exemplified by two marketed drugs

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Anti-dengue drug: A medical mystery - RAPPLER

Details: Anti-dengue drug: A medical mystery. This medical mystery may yet turn out to be a real horror story, where an unethical drug company and its local partners met …

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Trials on PH-made anti-dengue drug nearing completion

Details: Dengue, a mosquito-borne viral infection, is one of the most enduring health problems in the Philippines. However, that may soon change with the development of the first anti-dengue drug—created in the country. Pharmalytics Corporation, the company behind the venture, announced that the miracle medicine is nearing completion. According to Dr. Rita Grace Alvero and

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Anti-dengue drug developed by Filipinos may be available

Details: Anti-dengue drug developed by Filipinos may be available by 2020. Published December 21, 2019, 12:00 AM. by manilabulletin_admin. By Analou De Vera. A new anti-dengue drug developed by Filipino researchers may be available in the market by the end of 2020, experts said. Department of Health Secretary Francisco Duque III.

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First FDA-approved vaccine for the prevention of dengue

Details: The U.S. Food and Drug Administration announced today the approval of Dengvaxia, the first vaccine approved for the prevention of dengue disease caused by all dengue virus serotypes (1, 2, 3 and 4

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Biased efficacy estimates in phase-III dengue vaccine

Details: 1. PLoS One. 2019 Jan 25;14(1):e0210041. doi: 10.1371/journal.pone.0210041. eCollection 2019. Biased efficacy estimates in phase-III dengue vaccine trials due to heterogeneous exposure and differential detectability of primary infections across trial arms.

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Dengue compound backed by J&J shows potency against the

Details: An oral dengue drug developed by Johnson & Johnson's Janssen unit and a Belgian team was effective in mouse models, drastically lowering the …

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Researchers identify first drug that is effective against

Details: Researchers identify first drug that is effective against dengue infection. Belgium: A recent study reported in the journal Nature has described a new target for the treatment of dengue. The antiviral compound showed strong activity in mice for prophylaxis against dengue

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Sun Pharma's plant-based under trial dengue drug could be

Details: New Delhi: Sun Pharmaceutical, the country’s largest drug maker, may soon test its “plant-based” drug — which is still in the trial stage and meant for the treatment of dengue — to see if it can treat Covid-19 patients.. The Mumbai-based manufacturer of Revital tablets and Volini gel has been developing the phytochemical-based drug to treat dengue for the last four years.

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Antiviral Research and Development Against Dengue Virus

Details: The cellular targets for antiviral research against dengue 18 siRNAs as tools and/or therapeutic agents 19 Response modifiers 20 Monoclonal antibodies 21 Mechanical devices 21 Part 3. Academic and academy-associated research centers 22 Part 4. The current industrial network of AV discovery 31 Part 5. Mapping the dengue drug design effort and

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Antiviral activity of silymarin and baicalein against

Details: Dengue is an arthropod-borne viral disease that has become endemic and a global threat in many countries with no effective antiviral drug available currently. This study showed that flavonoids

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Dengue Antiviral Development: A Continuing Journey.

Details: The path to successful dengue drug development depends on availability of relevant preclinical testing models and better understanding of dengue pathogenesis. In recent years, efforts to develop dengue therapeutics have focused on both repurposing approved drugs as well as discovery of new chemical entities that act via virus or host targeted

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Discovering Dengue Drugs - Together - Phase 2 Research

Details: Mission. The mission of Discovering Dengue Drugs - Together - Phase 2 is to identify promising drug candidates to combat the Dengue, Hepatitis C, West Nile, Yellow Fever, and other related viruses. The extensive computing power of World Community Grid will be used to complete the structure-based drug discovery calculations required to identify

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Sun Pharma gets approval to test plant-based dengue drug

Details: Dengue drug to be repurposed AQCH has shown broad antiviral effect in in-vitro studies and is, hence, being tested as a potential treatment option for Covid-19, the company said. Since 2016, Sun Pharma has been working very closely with the Department of Biotechnology (DBT), which functions under the Ministry of Science and Technology, to

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Scientists Develop Anti-viral Drug to Treat Dengue

Details: Scientists at Lucknow-based Central Drug Research Institute (CSIR-CDRI) claim to have developed a medicine to treat dengue, as per the Hindustan Times' sister publication Livehindustan.

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Anti-dengue drug: viral polyprotein, a potential target DDDT

Details: Anti-dengue drug: viral polyprotein, a potential target Syed Uzair Mahmood, Maryam Mushtaq, Maryam Jamil Syed Sindh Medical College, Jinnah Sindh Medical University, Karachi, PakistanWe would like to add our views regarding the article “Identification of covalent active site inhibitors of dengue virus protease” by Koh-Stenta et al.1 The article suggests the development of a possible drug

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Dengue vaccine - Wikipedia

Details: Dengue vaccine is a vaccine used to prevent dengue fever in humans. Development of dengue vaccines began in the 1920s, but was hindered by the need to create immunity against all four dengue serotypes.. As of 2021, one version is commercially available, known as CYD-TDV, and sold under the brand name Dengvaxia. The vaccine is only recommended in those who have previously had dengue

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Herbal remedies, vaccines and drugs for dengue fever

Details: Sofosbuvir is a drug which is used for hepatitis but research has been going on to check its efficacy for the treatment of dengue fever by using in silico and in vitro methods. Evaluation of GS-461203 which is an active metabolite of sofosbuvir was done by molecular docking analyses.

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Discovering Dengue Drugs – Together Research

Details: The mission of Discovering Dengue Drugs – Together is to identify promising drug leads to combat the Dengue, Hepatitis C, West Nile, Yellow Fever, and other related viruses. The extensive computing power of World Community Grid will be used to complete the structure-based drug discovery calculations required to identify these leads.

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KU Leuven researchers develop an ultrapotent inhibitor of

Details: The antiviral drug will be developed in an easy-to-administer formulation that can be optimised for the treatment and prevention of the disease in dengue

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Drug combination defeats dengue, Ebola in mice News

Details: To develop a potential antiviral treatment, Stanford researchers adopted an unusual approach: Rather than trying to disable viral enzymes, they targeted proteins the …

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Search Orphan Drug Designations and Approvals

Details: 4. -. Generic Name: N- (9-methoxynonyl)-1-deoxynojirimycin hydrochloride. Date Designated: 11/17/2014. Orphan Designation: Treatment of acute dengue illness (inclusive of acute dengue illness, dengue fever, dengue hemorrhagic fever, and dengue shock syndrome) Orphan Designation Status:

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Small molecule fights dengue in mice

Details: “A drug for treatment and prophylaxis of dengue fever may be within reach,” Christoph Nitsche says in an email. Nitsche, who studies dengue virus therapies at the Australian National

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Dengue Fever Michigan Medicine

Details: Dengue (say "DEN-gay") fever is a disease caused by a virus that is carried by mosquitoes. Mild cases cause a rash and flu-like symptoms. Some people, especially children, can get more serious forms of the illness, known as dengue hemorrhagic fever and dengue shock syndrome.

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Vaccines and immunization: Dengue

Details: There is a growing public health need for effective preventive interventions against dengue, a disease caused by four viruses, termed serotypes 1-4. A safe, effective and affordable dengue vaccine against the four strains would represent a major advance for the control of the disease and could be an important tool for reaching the WHO goal of

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IN-SILICO DOCKING OF BIOACTIVE COMPOUNDS DERIVED …

Details: drugs for dengue infections. INTRODUCTION: Dengue virus is considered an important mosquito-borne virus worldwide and possesses health care issue nowadays. Dengue infection become a serious health concern globally due to the high mortality rate and has no specific

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