Ezetimibe Drug

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Ezetimibe Uses, Dosage, Side Effects - Drugs.com

Details: Ezetimibe tablets are used to treat high cholesterol. Ezetimibe work to reduce the amount of cholesterol your body absorbs. It does not help you lose weight and ezetimibe has not been shown to prevent heart disease or heart attacks. Ezetimibe is used in patients who cannot control their cholesterol levels by diet and exercise alone. ezetimibe drug interaction

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Ezetimibe Oral: Uses, Side Effects, Interactions, Pictures

Details: Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood.Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates side effects of ezetimibe

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Ezetimibe: Uses, Interactions, Mechanism of Action

Details: The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating the effect of ezetimibe on intestinal cholesterol absorption. 3 Ezetimibe is used as an ezetimibe drug information

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Zetia (ezetimibe): Basics, Side Effects & Reviews

Details: Zetia (ezetimibe) typically has fewer side effects and drug interactions than statins. However, the muscle damage that can occur from taking a statin has also been reported in … prescription drug ezetimibe

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Ezetimibe C24H21F2NO3 - PubChem

Details: Ezetimibe C24H21F2NO3 CID 150311 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ezetimibe uses

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Ezetimibe: Side Effects, Dosage, Uses, and More

Details: Ezetimibe oral tablet is a prescription medication used to reduce high cholesterol levels. It’s available as a generic drug and as the brand-name drug Zetia. Ezetimibe is … ezetimibe 10 mg used for

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Zetia: Uses, Dosage & Side Effects Information - Drugs.com

Details: Other drugs may interact with ezetimibe, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Zetia drug interactions (more detail) Popular FAQ. Is it a statin drug/medication? No, Zetia is not a statin drug. Zetia reduces blood cholesterol in a different way zetia or ezetimibe

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Ezetimibe: MedlinePlus Drug Information

Details: Ezetimibe is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of medications called cholesterol-lowering medications.

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Ezetimibe (Oral Route) Side Effects - Mayo Clinic

Details: Side Effects. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

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Ezetimibe: Generic, Uses, Side Effects, Dosages

Details: Ezetimibe is a prescription drug used as therapy with lipid-altering agents and should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia.

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Drugs Similar To Ezetimibe and Similar Products and

Details: Lipitor (atorvastatin) and Zetia (ezetimibe) are used to lower cholesterol levels in the blood. Lipitor and Zetia belong to different drug classes. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain.

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Common and Rare Side Effects for ezetimibe oral

Details: The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of …

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Ezetimibe-Simvastatin Oral: Uses, Side Effects

Details: Uses. This combination medication is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. Ezetimibe

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Buy Zetia (Ezetimibe) Online Lowest Prices on all

Details: Buy Zetia (Ezetimibe) online, safe and convenient ordering procedure. Compare brand & generic prices online. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood.

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Ezetimibe: a review of its metabolism, pharmacokinetics

Details: Ezetimibe is the first lipid-lowering drug that inhibits intestinal uptake of dietary and biliary cholesterol without affecting the absorption of fat-soluble nutrients. Following oral administration, ezetimibe is rapidly absorbed and extensively metabolised (>80%) to the pharmacologically active ezetimibe-glucuronide.

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ezetimibe (Zetia) Uses, Side Effects & Dosage

Details: Ezetimibe is an oral drug that is used for the treatment of elevated blood cholesterol.The most commonly used class of drugs for lowering cholesterol levels, the statins, act by preventing the production of cholesterol by the liver.Ezetimibe has a different mechanism of action and lowers blood cholesterol by reducing the absorption of cholesterol from the intestine.

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Zetia (ezetimibe) dosing, indications, interactions

Details: USES: Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of …

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ezetimibe oral Interactions with Other Medication

Details: Drugs & Medications ; ezetimibe ; Medication Interactions ; ezetimibe Common Brand(s): Zetia Generic Name(s): ezetimibe . View Free Coupon .

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Ezetimibe Nature Reviews Drug Discovery

Details: Ezetimibe (Zetia), the first in a new class of agents that inhibit cholesterol absorption in the intestine, was approved by the FDA in October 2002 for the reduction of cholesterol levels in

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Zetia (ezetimibe) Information FDA

Details: Zetia (ezetimibe) is a medicine used to lower levels of total cholesterol and LDL (bad) cholesterol in the blood. Adverse reactions or quality problems experienced with …

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Ezetimibe: the first in a novel class of selective

Details: Zetia (ezetimibe) is the first medication in the novel class of selective cholesterol-absorption inhibitors to be released in the United States. Ezetimibe selectively inhibits the uptake of cholesterol from the intestinal lumen at the level of the enterocyte in …

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Zetia (Ezetimibe Tablets): Uses, Dosage, Side Effects

Details: Ezetimibe and ezetimibeglucuronide are the major drug-derived compounds detected in plasma, constituting approximately 10 to 20% and 80 to 90% of the total drug in plasma, respectively. Both ezetimibe and ezetimibe-glucuronide are eliminated from plasma with a half-life of approximately 22 hours for both ezetimibe and ezetimibeglucuronide.

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ezetimibe oral (Zetia Oral) Drug Interactions - Serious

Details: Medications known to have serious interactions with ezetimibe oral. Brand Names Include: Zetia Oral. All generic drug interactions for ezetimibe oral (lists will include brand and generic names): 2 significant drug interactions. 7 minor drug interactions.

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Effects of ezetimibe, a new cholesterol absorption

Details: Aims: This randomized, double-blind, placebo-controlled, parallel-group study evaluated the safety and efficacy of ezetimibe 10 mg/day in patients with primary hypercholesterolemia. Methods and results: Following dietary stabilization, a 2-12-week washout period, and a 4-week, single-blind, placebo lead-in period, 827 patients with baseline low-density lipoprotein …

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Zetia (ezetimibe): Side effects, generic, dosage, uses

Details: Zetia is a brand-name drug that contains the active drug ezetimibe. This active drug is also available as a generic medication. A generic drug is an exact copy of the active drug in a brand-name

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DailyMed - EZETIMIBE tablet

Details: Ezetimibe and ezetimibe-glucuronide are the major drug-derived compounds detected in plasma, constituting approximately 10% to 20% and 80% to 90% of the total drug in plasma, respectively. Both ezetimibe and ezetimibe-glucuronide are eliminated from plasma with a half-life of approximately 22 hours for both ezetimibe and ezetimibe-glucuronide.

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The pharmacokinetics of ezetimibe - PubMed

Details: Ezetimibe is the first member of a new class of selective cholesterol absorption inhibitors. The drug and its active glucuronide metabolite impair the intestinal reabsorption of both dietary and hepatically excreted biliary cholesterol through inhibition of a …

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Ezetimibe: a medicine used to treat high blood cholesterol

Details: Ezetimibe is a type of medicine used to lower cholesterol. It's used to treat high blood cholesterol. This is when you have too much of a fatty substance called cholesterol in your blood. You may also be prescribed ezetimibe if you cannot take cholesterol-lowering medicines called statins, or if statins do not work for you.

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Zetia (ezetimibe) dose, indications, adverse effects

Details: Ezetimibe and ezetimibe-glucuronide are the major drug-derived compounds detected in plasma, constituting approximately 10% to 20% and 80% to 90% of the total drug in plasma, respectively. Both ezetimibe and ezetimibe-glucuronide are slowly eliminated from the plasma with a half-life of about 22 hours.

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Ezetimibe (Oral Route) Description and Brand Names - Mayo

Details: Drug information provided by: IBM Micromedex. US Brand Name. Zetia; Descriptions. Ezetimibe is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. Using this medicine may help prevent medical problems caused by such substances clogging the blood vessels.

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Common and Rare Side Effects for ezetimibe oral

Details: The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of …

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Ezetimibe (Zetia) Davis’s Drug Guide

Details: 1. Download the Davis's Drug Guide app by Unbound Medicine. 2. Select Try/Buy and follow instructions to begin your free 30-day trial. You can cancel anytime within the 30-day trial, or continue using Davis's Drug Guide to begin a 1-year subscription ($39.95) ezetimibe. General.

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ZETIA - Food and Drug Administration

Details: In humans, ezetimibe is rapidly metabolized to ezetimibe-glucuronide. Ezetimibe and ezetimibe-glucuronide are the major drug-derived compounds detected in plasma, constituting approximately 10 to 20% and 80 to 90% of the total drug in plasma, respectively. Both ezetimibe and ezetimibe-glucuronide

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EZETIMIBE Drug BNF content published by NICE

Details: Drug action Ezetimibe inhibits the intestinal absorption of cholesterol. If used alone, it has a modest effect on lowering LDL-cholesterol, with little effect on other lipoproteins.

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Inhibition of intestinal cholesterol absorption decreases

Details: Nevertheless, ezetimibe treatment led to a striking (>85%) reduction in atherosclerotic lesion area with reduced lesion lipid and macrophage content in the HFHS+C group. Thus, in the presence of dietary cholesterol, ezetimibe did not improve adipose tissue inflammation in obese Ldlr(-/-) mice, but it led to a major reduction in atherosclerotic

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ezetimibe drug - MedHelp

Details: The FDA-approved drug ezetimibe (sold under the trade-name Zetia) is readily available and perfectly targeted to the receptor, Sainz said, so the researchers had an ideal method for testing NPC1L1's involvement in HCV infection. The researchers showed that ezetimibe inhibited HCV infection in cell culture and in mice transplanted with human liver cells.

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Serious drug-induced liver disease secondary to ezetimibe

Details: Ezetimibe is the first member of a new family of lipid-lowering drugs that inhibits uptake of dietary and biliary cholesterol. It was approved by the FDA in 2002 for hypercholesterolemia alone or in combination with statins. Its use has been spreading over the last years. Ezetimibe was considered a safe drug.

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Ezetimibe Davis's Drug Guide for Rehabilitation

Details: Drug-Drug: Effects may be ↓ by cholestyramine or other bile acid sequestrants. Concurrent use of fibrates may ↑ blood levels of ezetimibe and also ↑ the risk of cholelithiasis. Cyclosporine may ↑

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Melanin: Production from Cheese Bacteria, Chemical

Details: On the other side, the simultaneous administration to the cells of melanin with the drug ezetimibe did not reduce the cholesterol permeation in a substantial amount, which is a 10% reduction in the drug effect. 4. Discussion. 4.1. Production and Structural Analysis.

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Ezetimibe - Drug Usage Statistics, ClinCalc DrugStats Database

Details: Ezetimibe drug usage statistics for the United States (2013 - 2019). Statistics include drug synonyms and therapeutic classes, including: Ezetimibe, Zetia, Dietary Cholesterol Absorption Inhibitor.

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Adding ezetimibe to statin therapy: latest evidence and

Details: Ezetimibe is a cholesterol-lowering drug from the class of cholesterol absorption inhibitors, with the potency to decrease LDL-C by about 10–18% and Apo B by 11–16%, while in combination therapy with statins, an additional LDL-C lowering of 25% or total LDL-C lowering of 34–61% is observed.

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EZETIMIBE Cost Comparison - Find The Best EZETIMIBE Price

Details: EZETIMIBE (ez ET i mibe) treats high cholesterol. It works by reducing the amount of cholesterol absorbed from the food you eat. This decreases the amount of …

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10.1016/j.metabol.2006.08.013 10.1016/j - DeepDyve

Details: The prototype bile acid–binding resin, cholestyramine, binds numerous drugs nonspecifically, including ezetimibe in vitro [9,21] . In vivo, ezetimibe bioavailability is reduced to 45% of control when cholestyramine is given 1 or 13 hours after ezetimibe administration.

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Ezetimibe Interaction with Food, Herbs and Alcohol

Details: Ezetimibe Interactions with Food and Herbs Grapefruit Juice: Ezetimibe interacts with grapefruit juice. Grapefruit juice increases the drug levels in the blood stream potentially leading to side

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Ezetimibe: Indication, Dosage, Side Effect, Precaution

Details: Description: Ezetimibe localises at the brush border of the small intestine and inhibits absorption of cholesterol via the sterol transporter, Niemann-Pick C1-Like1 (NPC1L1).This results in decreased delivery of cholesterol to the liver, reduction of hepatic cholesterol stores and increased clearance of cholesterol from the blood.

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DGIdb - EZETIMIBE Drug Record

Details: Wang et al., 2005, Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe., Clin. Genet. Altmann et al., 2004, Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption., Science

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