Simvastatin Drug

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Simvastatin Uses, Dosage & Side Effects - Drugs.com

Details: Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood). side effects of statin drugs

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Simvastatin Oral: Uses, Side Effects, Interactions

Details: Simvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood.It belongs to a group of drugs simvastatin drug interactions

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Simvastatin Side Effects, Dosage, Usage, and More

Details: Simvastatin is a prescription drug. It comes in two forms: a tablet and a suspension. Both forms are taken by mouth. Simvastatin oral tablet is available as the brand-name drug Zocor… medicine simvastatin 20 mg

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Statin side effects: Weigh the benefits and risks - Mayo

Details: Switch to another statin drug. It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other … statins for cholesterol

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Examining the Nocebo Effect of Statins Through Statin

Details: astatin, pravastatin, rosuvastatin, and simvastatin, the most commonly used statin products on the market.10 We also separately analyzed simvastatin compared with other statins. Since simvastatin is the most lipophilic statin, it is most likely to be associated with muscular AEs based on the PRIMO study. 11 statin drugs

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Lovastatin Davis Drug Guide - druglist.info

Details: Simvastatin Davis Drug Guide. Health (1 days ago) Simvastatin Davis Drug Guide Pdf. Health (5 days ago) Davis’s Drug Guide simvastatin.Health (2 days ago) simvastatin was found in Davis’s Drug Guide.Davis’s Drug Guide for Nurses App + Web from F.A. Davis and Unbound Medicine covers 5000+ trade name and generic drugs.Includes App for iPhone, iPad, and Android smartphone + tablet. drug simvastatin for cholesterol control

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simvastatin oral Interactions with Other Medication

Details: Does SIMVASTATIN Interact with other Medications? Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more list of statins

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Simvastatin - Drug

Details: Simvastatin, a prodrug, is converted to its active metabolite simvastatin acid (SVA), which is a substrate of the organic anion transporter protein OATP1B1. OATP1B1 mediates the hepatic uptake of statins and other endogenous compounds (e.g. bilirubin) for subsequent elimination.

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Simvastatin: Generic, Uses, Side Effects, Dosages

Details: Simvastatin is a, FDA approved prescription medication that is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol in the blood.It belongs to a group of drugs known as "statins."Statins are medications that work by reducing the amount of cholesterol made by the liver.

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Simvastatin (Oral Suspension): Uses, Dosage, Side Effects

Details: Simvastatin is a white to off-white, nonhygroscopic, crystalline powder that is practically insoluble in water, and freely soluble in chloroform, methanol and ethanol.. Simvastatin Oral Suspension contains either 20 mg of simvastatin per 5 mL (corresponding to 4 mg per mL) or 40 mg of simvastatin per 5 mL (corresponding to 8 mg per mL) and the following inactive ingredients: acesulfame

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Simvastatin (Zocor): Basics, Side Effects & Reviews

Details: Simvastatin (Zocor) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.

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Simvastatin: Uses, Interactions, Mechanism of Action

Details: Generic Name Simvastatin DrugBank Accession Number DB00641 Background. Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus.It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the …

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Simvastatin Information FDA

Details: Simvastatin is a medication included in the class of drugs called statins. Statin drugs are used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol

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Dangers of Statin Drugs: What You Haven’t Been Told About

Details: Statin drugs are very expensive–a course of statins for a year costs between $900 and $1400. They constitute the mostly widely sold pharmaceutical drug, accounting for 6.5 percent of market share and 12.5 billion dollars in revenue for the industry. Your insurance company may pay most of that cost, but consumers always ultimately pay with

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FDA Drug Safety Communication: New restrictions

Details: Patients taking simvastatin 80 mg daily have an increased risk of myopathy compared to patients taking lower doses of this drug or other drugs in the same class.

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Zocor (simvastatin) Uses, Side Effects, Dosage & Interactions

Details: any other cholesterol medication--niacin, fenofibrate, fenofibric acid, and others; or; a blood thinner--warfarin, Coumadin, Jantoven. This list is not complete and many other drugs may affect simvastatin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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Drug Interactions with Simvastatin: The Risk Continues

Details: A number of drugs are known to inhibit OATP1b1 (eg, clarithromycin, erythromycin, cyclosporine, ketoconazole, many protease inhibitors, gemfibrozil) and are known to increase simvastatin concentrations. 5 Note that many OATP1b1 inhibitors are also CYP3A4 inhibitors, which provides the opportunity for a dual mechanism drug interaction with

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Simvastatin C25H38O5 - PubChem

Details: Simvastatin is a member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.It has a role as an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, a prodrug, an EC 1.1.1.34/EC 1.1.1.88

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A new therapeutic effect of simvastatin revealed by

Details: Simvastatin dramatically reduced damage and enhanced muscle function in dystrophic (mdx) mice. Long-term simvastatin treatment vastly improved overall muscle health in mdx mice, reducing plasma creatine kinase activity, an established measure of muscle damage, to near-normal levels. This reduction was accompanied by reduced inflammation, more

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Simvastatin - StatPearls - NCBI Bookshelf

Details: Simvastatin is an oral HMG-CoA reductase inhibitor indicated as an adjunct to diet. It is a semi-synthetic derivative of lovastatin, the first FDA-approved statin. Simvastatin helps lower cholesterol production and reduce dyslipidemia-associated complications. High concentrations of LDL cholesterol can lead to artery damage, potentially leading to cardiac complications and stroke.

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Simvastatin - Side Effects, Uses, Dosage, Overdose

Details: Simvastatin is a prescription medication used to treat high cholesterol, high triglycerides, and disease of the heart and blood vessels. Simvastatin belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins. It works by blocking the production of cholesterol in the body.

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simvastatin Nursing Considerations & Management - RNpedia

Details: Drug Name Generic Name : simvastatin Brand Name: Apo-Simvastatin (CAN), Gen-Simvastatin (CAN), CO Simvastatin (CAN), Novo-Simvastatin (CAN), ratio-Simvastatin (CAN), Zocor Classification: Antihyperlipidemic, HMG-CoA reductase inhibitor Pregnancy Category X Dosage & Route Available forms : Tablets—5, 10, 20, 40, 80 mg ADULTS Initially, 20 mg PO; up to 80 mg PO daily in …

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Simvastatin provides long-term improvement of left

Details: Recently, we demonstrated that simvastatin substantially improved skeletal muscle health and function in mdx (DMD) mice. Given the known cardiovascular benefits ascribed to statins, the aim of this study was to evaluate the efficacy of simvastatin on cardiac function in mdx mice.

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Simvastatin (FloLipid, Zocor) Davis’s Drug Guide

Details: 1. Download the Davis's Drug Guide app by Unbound Medicine. 2. Select Try/Buy and follow instructions to begin your free 30-day trial. You can cancel anytime within the 30-day trial, or continue using Davis's Drug Guide to begin a 1-year subscription ($39.95) simvastatin. General. Indications.

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ZOCOR (simvastatin) Tablets - Food and Drug Administration

Details: myopathy. Simvastatin therapy should be discontinued immediately if myopathy is diagnosed or suspected. See Drug Interaction table. (5.1) • Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminase can occur. Monitor liver enzymes before and during treatment. Patients titrated to the 80-mg dose should receive

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Zocor (simvastatin): Statin Uses, Side Effects & Dosage

Details: Zocor (simvastatin) is a drug prescribed to reduce triglycerides, total cholesterol (LDL), and increasing HDL cholesterol. Common side effects of Zocor include diarrhea, vomiting, headache, and abdominal pain. Zocor belongs to the drug class of Statins. Uses and dosage information are provided.

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Statin - Wikipedia

Details: Simvastatin (Zocor) was approved as a generic drug in the US in June 2006. Atorvastatin (Lipitor) was approved as a generic drug in the US in November 2011. Fluvastatin (Lescol) was approved as a generic drug in the US in April 2012. Pitavastatin (Livalo) and rosuvastatin (Crestor) were approved as generic drugs in the US in 2016.

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[Medication management: Simvastatin and Amlodipin - a

Details: The clinical relevance of the drug-drug interaction simvastatin and amlodipine is appraised controversially by german simvastatin Summary of Product Characteristics (SPCs) and different drug interaction databases. Results of clinical trials have shown that simultaneous administration of simvastatin

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Zocor (simvastatin) dose, indications, adverse effects

Details: Simvastatin is a sensitive CYP3A4 substrate and ceritinib is a strong CYP3A4 inhibitor. Chlorzoxazone: (Moderate) One case report has noted a possible drug interaction between simvastatin and chlorzoxazone. Rhabdomyolysis, slight renal insufficiency and cholestatic hepatitis occurred in a 73-year old woman 14 days after chlorzoxazone was added

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Simvastatin Drug Information - Indications, Dosage, Side

Details: This medication is an HMG-CoA reductase inhibitor, also known as a "statin", used for lowering high cholesterol and triglycerides in certain patients with appropriate diet.

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Simvastatin - an overview ScienceDirect Topics

Details: Simvastatin, a FDA approved drug that specifically inhibits HMG-CoA reductase, is a widely prescribed drug to lower LDL cholesterol and triglyceride levels in hyperlipidemia subjects with proven beneficial effects in coronary artery disease. In addition to lipid-lowering property,

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Simvastatin and Cannabis drug interactions, a phase IV

Details: Summary: Drug interactions are reported among people who take Simvastatin and Cannabis. Common interactions include blister among females and dyspnoea among males. The phase IV clinical study analyzes what interactions people who take Simvastatin and Cannabis have. It is created by eHealthMe based on reports of 39 people who take Simvastatin

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simvastatin Pictures & Common Dosing - WellRx

Details: SIMVASTATIN (SIM va stat in) is a statin. It lowers bad cholesterol and triglyceride levels in the blood. It also increases good cholesterol levels. It is used with lifestyle changes, like diet and exercise. It may be used alone or with other drugs.

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ZOCOR (simvastatin) Tablets - Food and Drug Administration

Details: need to be initiated on an interacting drug that is contraindicated or is associated with a dose cap for simvastatin should be switched to an alternative statin with less potential for the drug-drug interaction. (2.2) • Due to the increased risk of myopathy, including rhabdomyolysis, associated with the 80-mg dose of ZOCOR, patients unable to

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Statins do not lower risk for death from COVID-19, but may

Details: 1 day ago · Use of statin drugs such as rosuvastatin, sold as Crestor, and atorvastatin, or Lipitor, did not lower hospitalized patients' risk for death from COVID-19, the data showed.

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Simvastatin and Ibuprofen drug interactions, a phase IV

Details: Drug interactions are reported among people who take Simvastatin and Ibuprofen. Common interactions include diarrhoea among females and chronic kidney disease among males. The phase IV clinical study analyzes what interactions people who take Simvastatin and Ibuprofen have.

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Side Effects of Zocor (simvastatin): Interactions & Warnings

Details: Zocor (simvastatin) is a cholesterol-lowering drug called an HMG-CoA reductase inhibitor (a “statin”) used to reduce total cholesterol, LDL cholesterol, and triglycerides, and to increase HDL cholesterol.. In patients with coronary heart disease, diabetes, peripheral vascular disease, or history of stroke or other cerebrovascular disease, simvastatin is prescribed for reducing the risk of

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ZOCOR Dosage & Rx Info Uses, Side Effects

Details: Restrict 80mg/day dose to chronic users (≥12mos) without evidence of muscle toxicity; if currently tolerating simvastatin 80mg and need to start a contraindicated drug or is associated with a

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Simvastatin PeaceHealth

Details: Drug Information. Simvastatin is a member of the HMG-CoA reductase inhibitor family of drugs that blocks the body's production of cholesterol. Simvastatin is used to lower high cholesterol and to reduce the risk of heart attack and death.

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