Bnf.nice.org.uk View all drugs

Respiratory system, drug delivery Treatment summary

Details: Drugs given by mouth for the treatment of asthma include corticosteroids, theophylline, and leukotriene receptor antagonists. Parenteral Drugs such as beta 2 agonists, corticosteroids, and aminophylline can be given by injection in severe acute and life-threatening asthma when administration by nebulisation is inadequate or inappropriate.

› Verified 9 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/respiratory-system-drug-delivery.html Go Now

• Get more: Bnf drugsGo Now

Adverse reactions to drugs

Details: " }, "rdfs:label": "controlled drugs and drug dependence" }, { "@id": "http://bnf.nice.org.uk/guidance/prescribing-in-renal-impairment", "hasTitle": { "@type": "rdf

› Verified 3 days ago

› Url: https://bnf.nice.org.uk/guidance/index.json Go Now

• Get more: Bnf ukGo Now

Anaesthesia (general) Treatment summary BNF content

Details: Drugs used for intravenous anaesthesia. Propofol, the most widely used intravenous anaesthetic, can be used for induction or maintenance of anaesthesia in adults and children, but it is not commonly used in neonates. Propofol is associated with rapid recovery and less hangover effect than other intravenous anaesthetics. Propofol can also be used for sedation during diagnostic …

› Verified 6 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/anaesthesia-general.html Go Now

• Get more: Bnf for childrenGo Now

Anaesthesia (local) Treatment summary BNF content

Details: Local anaesthetic drugs. The use of local anaesthetics by injection or by application to mucous membranes to produce local analgesia is discussed in this section. Local anaesthetic drugs act by causing a reversible block to conduction along nerve fibres. They vary widely in their potency, toxicity, duration of action, stability, solubility in

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/anaesthesia-local.html Go Now

› Get more:  DoctorGo Now

nitrates Drug class BNF content published by NICE

Details: Many patients on long-acting or transdermal nitrates rapidly develop tolerance (with reduced therapeutic effects). Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. If tolerance is suspected during the use of transdermal patches they should be left off for 8–12

› Verified Just Now

› Url: https://bnf.nice.org.uk/drug-class/nitrates-2.html Go Now

› Get more:  DoctorGo Now

Pain, Chronic Treatment summary BNF content published

Details: Drug treatment. A variety of analgesics are used in the treatment of chronic pain and can be divided into non-opioid, opioid, and adjuvant analgesics. Although developed and validated for cancer pain, the WHO analgesic ladder is widely used to guide the basic treatment of acute and chronic pain; whilst there is little evidence to support its use in chronic pain it may provide an …

› Verified 9 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/pain-chronic.html Go Now

› Get more:  CancerGo Now

Neuromuscular disorders Treatment summary BNF content

Details: Drugs that enhance neuromuscular transmission. Anticholinesterases are used as first-line treatment in ocular myasthenia gravis and as an adjunct to immunosuppressant therapy for generalised myasthenia gravis.. Corticosteroids are used when anticholinesterases do not control symptoms completely.

› Verified Just Now

› Url: https://bnf.nice.org.uk/treatment-summary/neuromuscular-disorders.html Go Now

› Get more:  DoctorGo Now

Mydriatics and cycloplegics Treatment summary BNF

Details: Phenylephrine hydrochloride is a sympathomimetic licensed for mydriasis in diagnostic or therapeutic procedures. Mydriasis occurs within 60–90 minutes and lasts up to 5–7 hours. Mydriatics and cycloplegics are used in the treatment of anterior uveitis, usually as an adjunct to corticosteroids. Atropine sulfate or cyclopentolate

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/mydriatics-and-cycloplegics.html Go Now

› Get more:  DoctorGo Now

Prescribing in breast-feeding Medicines guidance BNF

Details: For many drugs insufficient evidence is available to provide guidance and it is advisable to administer only essential drugs to a mother during breast-feeding. Because of the inadequacy of information on drugs in breast-feeding, absence of information does not imply safety.

› Verified 7 days ago

› Url: https://bnf.nice.org.uk/guidance/prescribing-in-breast-feeding.html Go Now

› Get more:  DoctorGo Now

COVID-19 Treatment summary BNF content published by NICE

Details: Drug treatment. Individuals with COVID‑19 have an increased risk of venous thromboembolism (VTE). For further guidance on VTE prophylaxis and management in patients with COVID‑19, see NICE rapid guideline: Managing COVID‑19 (see Useful resources) and SIGN position statement: The prevention and management of thromboembolism in hospitalised patients with COVID-19 …

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/covid-19.html Go Now

› Get more:  DoctorGo Now

KETAMINE Drug BNF content published by NICE

Details: For information on 2015 legislation regarding driving whilst taking certain controlled drugs, including ketamine, see Drugs and driving under Guidance on prescribing. Medicinal forms. There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension

› Verified 2 days ago

› Url: https://bnf.nice.org.uk/drug/ketamine.html Go Now

› Get more:  DoctorGo Now

Emergency supply of medicines Medicines guidance BNF

Details: that no greater quantity shall be supplied than will provide 5 days’ treatment of phenobarbital, phenobarbital sodium, or Controlled Drugs in Schedules 4 or 5 (doctors, dentists, or nurse prescribers from the European Economic Area and Switzerland, or their patients, cannot request an emergency supply of Controlled Drugs in Schedules 1, 2, or

› Verified 7 days ago

› Url: https://bnf.nice.org.uk/guidance/emergency-supply-of-medicines.html Go Now

› Get more:  DoctorGo Now

Hyperparathyroidism Treatment summary BNF content

Details: Hyperparathyroidism, primary. Primary hyperparathyroidism is a disorder of the parathyroid glands—most commonly caused by a non-cancerous tumour (adenoma) in one of the glands. The resulting excess secretion of parathyroid hormone leads to hypercalcaemia, hypophosphataemia and hypercalciuria. The main symptoms are a result of hypercalcaemia

› Verified 6 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/hyperparathyroidism.html Go Now

› Get more:  CancerGo Now

fibrinolytics Drug class BNF content published by NICE

Details: Thrombolytic drugs can possibly lead to premature separation of the placenta in the first 18 weeks of pregnancy. There is also a risk of maternal haemorrhage throughout pregnancy and post-partum, and also a theoretical risk of fetal haemorrhage throughout pregnancy.

› Verified 3 days ago

› Url: https://bnf.nice.org.uk/drug-class/fibrinolytics.html Go Now

› Get more:  DoctorGo Now

benzodiazepines Drug class BNF content published by NICE

Details: The MHRA reminds healthcare professionals that benzodiazepines and benzodiazepine-like drugs co-prescribed with opioids can produce additive CNS depressant effects, thereby increasing the risk of sedation, respiratory depression, coma, and death.

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/drug-class/benzodiazepines.html Go Now

› Get more:  DoctorGo Now

Guidance on intravenous infusions Medicines guidance

Details: Drugs should only be added to infusion containers when constant plasma concentrations are needed or when the administration of a more concentrated solution would be harmful. In general, only one drug should be added to any infusion container and the components should be compatible. Ready-prepared solutions should be used whenever possible.

› Verified 1 days ago

› Url: https://bnf.nice.org.uk/guidance/guidance-on-intravenous-infusions.html Go Now

› Get more:  DoctorGo Now

Hydroxychloroquine Interactions BNF content published

Details: A list of drugs that interact with Hydroxychloroquine. Both hydroxychloroquine and arsenic trioxide prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation.

› Verified 9 days ago

› Url: https://bnf.nice.org.uk/interaction/hydroxychloroquine.html Go Now

› Get more:  DoctorGo Now

Corticosteroids, inflammatory disorders Treatment

Details: In inflammatory conditions of the joints, particularly in rheumatoid arthritis, they are given by intra-articular injection to relieve pain, increase mobility, and reduce deformity in one or a few joints; they can also provide symptomatic relief while waiting for disease-modifying antirheumatic drugs (DMARDs) to take effect.

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/corticosteroids-inflammatory-disorders.html Go Now

› Get more:  DoctorGo Now

Anaemias Treatment summary BNF content published by NICE

Details: Ideally, information about G6PD deficiency should be available before prescribing drugs that are associated with a risk of haemolysis in G6PD-deficient patients, including those listed below. However, in the absence of this information, the possibility of haemolysis should be considered, especially if the patient belongs to a group in which

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/anaemias.html Go Now

› Get more:  DoctorGo Now

opioids Drug class BNF content published by NICE

Details: The MHRA reminds healthcare professionals that opioids co-prescribed with benzodiazepines and benzodiazepine-like drugs can produce additive CNS depressant effects, thereby increasing the risk of sedation, respiratory depression, coma, and death.

› Verified 7 days ago

› Url: https://bnf.nice.org.uk/drug-class/opioids.html Go Now

› Get more:  DoctorGo Now

Frequently asked questions—clinical About BNF content

Details: For example, we know that drugs with an adverse effect resulting in lowered blood pressure are likely to have additive effects with drugs used to manage hypotension. This data doesn’t come directly from investigating the interaction but is a logical result based on the known pharmacology of the drugs, and so no level of evidence has been applied.

› Verified 9 days ago

› Url: https://bnf.nice.org.uk/about/frequently-asked-questionsclinical.html Go Now

› Get more:  DoctorGo Now

Antacids Interactions BNF content published by NICE

Details: A list of drugs that interact with Antacids. Oral antacids are predicted to decrease the absorption of oral ibandronate.

› Verified 1 days ago

› Url: https://bnf.nice.org.uk/interaction/antacids-2.html Go Now

› Get more:  DoctorGo Now

Itraconazole Interactions BNF content published by NICE

Details: A list of drugs that interact with Itraconazole. Itraconazole is predicted to increase the exposure to beclometasone (risk with beclometasone is likely to be lower than with other corticosteroids).

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/interaction/itraconazole-2.html Go Now

› Get more:  DoctorGo Now

Phenytoin Interactions BNF content published by NICE

Details: A list of drugs that interact with Phenytoin. Intravenous chloramphenicol increases the concentration of phenytoin and phenytoin affects the concentration of intravenous chloramphenicol.

› Verified 2 days ago

› Url: https://bnf.nice.org.uk/interaction/phenytoin-2.html Go Now

› Get more:  DoctorGo Now

Gabapentin Interactions BNF content published by NICE

Details: A list of drugs that interact with Gabapentin. Both gabapentin and chloral hydrate can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing).

› Verified 3 days ago

› Url: https://bnf.nice.org.uk/interaction/gabapentin-2.html Go Now

› Get more:  DoctorGo Now

Tamsulosin Interactions BNF content published by NICE

Details: Avanafil. Both tamsulosin and avanafil can increase the risk of hypotension. Tamsulosin causes significant hypotensive effects when given with avanafil. Manufacturer advises patient should be stabilised on first drug then second drug should be added at the lowest recommended dose. Severity of interaction: Severe. Evidence for interaction:

› Verified 1 days ago

› Url: https://bnf.nice.org.uk/interaction/tamsulosin.html Go Now

› Get more:  DoctorGo Now

Smoking cessation Treatment summary BNF content

Details: Concomitant drugs. Polycyclic aromatic hydrocarbons found in tobacco smoke increase the metabolism of some drugs by inducing hepatic enzymes, often requiring an increase in dose. Information about drugs interacting with tobacco smoke can be found under Interactions of the relevant drug monograph.

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/smoking-cessation.html Go Now

› Get more:  DoctorGo Now

Magnesium Interactions BNF content published by NICE

Details: A list of drugs that interact with Magnesium. Intravenous magnesium potentially increases the risk of hypotension when given with felodipine in pregnant women.

› Verified Just Now

› Url: https://bnf.nice.org.uk/interaction/magnesium.html Go Now

› Get more:  DoctorGo Now

Salbutamol Interactions BNF content published by NICE

Details: A list of drugs that interact with Salbutamol. Salbutamol is predicted to cause hypokalaemia (potentially increasing the risk of torsade de pointes) when given with arsenic trioxide.

› Verified 3 days ago

› Url: https://bnf.nice.org.uk/interaction/salbutamol-2.html Go Now

› Get more:  DoctorGo Now

Hydroxyzine Interactions BNF content published by NICE

Details: Both hydroxyzine and encorafenib prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to …

› Verified 2 days ago

› Url: https://bnf.nice.org.uk/interaction/hydroxyzine.html Go Now

› Get more:  DoctorGo Now

Combined hormonal contraceptives Interactions BNF

Details: Combined hormonal contraceptives are predicted to increase the risk of venous thromboembolism when given with pomalidomide. Manufacturer advises avoid. Severity of interaction: Severe. Evidence for interaction: Theoretical.

› Verified 3 days ago

› Url: https://bnf.nice.org.uk/interaction/combined-hormonal-contraceptives.html Go Now

› Get more:  DoctorGo Now

Iron Interactions BNF content published by NICE

Details: A list of drugs that interact with Iron. Oral zinc is predicted to decrease the efficacy of oral iron and oral iron is predicted to decrease the efficacy of oral zinc.

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/interaction/iron.html Go Now

› Get more:  DoctorGo Now

Flucloxacillin Interactions BNF content published by NICE

Details: A list of drugs that interact with Flucloxacillin. Flucloxacillin potentially alters the anticoagulant effect of acenocoumarol.

› Verified 7 days ago

› Url: https://bnf.nice.org.uk/interaction/flucloxacillin-2.html Go Now

› Get more:  DoctorGo Now

Zolmitriptan Interactions BNF content published by NICE

Details: Fluvoxamine. Both zolmitriptan and fluvoxamine can increase the risk of serotonin syndrome. See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs in BNF for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs.

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/interaction/zolmitriptan-2.html Go Now

› Get more:  DoctorGo Now

Linezolid Interactions BNF content published by NICE

Details: Isocarboxazid. Both linezolid and isocarboxazid can increase the risk of serotonin syndrome. See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs in BNF for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs.

› Verified 2 days ago

› Url: https://bnf.nice.org.uk/interaction/linezolid-2.html Go Now

› Get more:  DoctorGo Now

Lithium Interactions BNF content published by NICE

Details: Both lithium and almotriptan can increase the risk of serotonin syndrome. See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs in BNF for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs.

› Verified 8 days ago

› Url: https://bnf.nice.org.uk/interaction/lithium.html Go Now

› Get more:  DoctorGo Now

Fentanyl Interactions BNF content published by NICE

Details: Brimonidine. Both fentanyl and brimonidine can increase the risk of bradycardia. Both fentanyl and brimonidine can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing ).

› Verified 1 days ago

› Url: https://bnf.nice.org.uk/interaction/fentanyl-2.html Go Now

› Get more:  DoctorGo Now

Alcohol dependence Treatment summary BNF content

Details: Alcohol dependence is a cluster of behavioural, cognitive and physiological factors that typically include a strong desire to drink alcohol, tolerance to its effects, and difficulties controlling its use. Someone who is alcohol-dependent may persist in drinking, despite harmful consequences, such as physical or mental health problems.

› Verified 5 days ago

› Url: https://bnf.nice.org.uk/treatment-summary/alcohol-dependence.html Go Now

› Get more:  DoctorGo Now

Flecainide Interactions BNF content published by NICE

Details: Both flecainide and apalutamide prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to …

› Verified 1 days ago

› Url: https://bnf.nice.org.uk/interaction/flecainide.html Go Now

› Get more:  DoctorGo Now

Mirtazapine Interactions BNF content published by NICE

Details: Tapentadol. Both mirtazapine and tapentadol can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing ). Tapentadol is predicted to increase the risk of serotonin syndrome when given with mirtazapine. Manufacturer advises caution.

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/interaction/mirtazapine-2.html Go Now

› Get more:  DoctorGo Now

Ciclosporin Interactions BNF content published by NICE

Details: A list of drugs that interact with Ciclosporin. Measles, mumps and rubella vaccine, live is predicted to increase the risk of generalised infection …

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/interaction/ciclosporin-2.html Go Now

› Get more:  DoctorGo Now

Alcohol Interactions BNF content published by NICE

Details: Clomethiazole. Both alcohol and clomethiazole can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing ). Alcohol causes serious, potentially fatal, CNS depression when given with clomethiazole. Manufacturer advises avoid.

› Verified Just Now

› Url: https://bnf.nice.org.uk/interaction/alcohol-2.html Go Now

› Get more:  DoctorGo Now

Articaine Interactions BNF content published by NICE

Details: A list of drugs that interact with Articaine. Both articaine and chloral hydrate can have CNS depressant effects, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing).

› Verified Just Now

› Url: https://bnf.nice.org.uk/interaction/articaine.html Go Now

› Get more:  DoctorGo Now

Dronedarone Interactions BNF content published by NICE

Details: Moxifloxacin. Both dronedarone and moxifloxacin prolong the QT interval. Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to QT prolongation.

› Verified 4 days ago

› Url: https://bnf.nice.org.uk/interaction/dronedarone-2.html Go Now

› Get more:  DoctorGo Now