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Compassionate Drug Use

Details: These drugs are normally available only to people who are taking part in a clinical trial. Being able to use one of these drugs when you are not in a clinical trial is most commonly referred to as compassionate drug use. Is compassionate drug use legal? Compassionate drug use is legal, but it’s limited to people who meet certain conditions.

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Medicines Used to Treat Nausea and Vomiting

Details: These drugs are effective at controlling acute nausea and vomiting and are usually given before chemo and then for a few days afterward. (Examples: Ondansetron, Granisetron, Dolasetron, Palonosetron) NK-1 receptor antagonists block the effects of the NK-1 receptor, a receptor that is a part of the vomiting reflex. These drugs help with delayed

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Targeted Therapy Drugs for Acute Myeloid Leukemia (AML)

Details: Targeted drugs called IDH inhibitors can block these IDH proteins. These drugs seem to work by helping the leukemia cells mature (differentiate) into more normal cells. Because if this, they are sometimes referred to as a differentiation agents. These drugs can be used to treat AML with an IDH1 or IDH2 mutation. Your doctor can test your blood

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How Chemotherapy Drugs Work

Details: Chemotherapy drugs target cells at different phases of the cell cycle. Understanding how these drugs work helps doctors predict which drugs are likely to work well together. Doctors can also plan how often doses of each drug should be given based on the timing of the cell phases.

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Targeted Therapy Drugs for Chronic Lymphocytic Leukemia

Details: Targeted therapies are drugs that specifically target the changes inside cells that cause them to become cancer. Unlike standard chemotherapy drugs, which work by attacking rapidly growing cells in general (including cancer cells), these drugs target one or more specific proteins on or in chronic lymphocytic leukemia (CLL) cells. When treatment is needed for CLL, a targeted drug is often part

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Melanoma Targeted Therapy Targeted Drugs for …

Details: These drugs target parts of melanoma cells that make them different from normal cells. Targeted drugs work differently from standard chemotherapy drugs, which basically attack any quickly dividing cells.. Targeted drugs can be very helpful in treating melanomas that have certain gene changes.

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Chemotherapy for Hodgkin Lymphoma Hodgkin …

Details: Chemotherapy (chemo) is the use of drugs to kill cancer cells. Chemo is usually injected into a vein under the skin or taken as a pill. Chemo drugs enter the bloodstream and travel throughout the body to reach and destroy cancer cells wherever they may be. Chemo is the main treatment for most people with Hodgkin lymphoma (other than some people

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Chemotherapy for Ewing Tumors American Cancer Society

Details: A combination of several chemo drugs is used to treat Ewing tumors. In the United States, the most common chemo regimen is known as VDC/IE (or VAC/IE ). It alternates between 2 combinations of drugs, given every 2 to 3 weeks: The first drug combination includes vincristine, doxorubicin (Adriamycin), and cyclophosphamide.

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Immune Checkpoint Inhibitors and Their Side Effects

Details: These drugs have also been shown to be helpful in treating different types of cancer, and are being studied for use against others. Checkpoint inhibitor drugs that target CTLA-4 CTLA-4 is another protein on some T cells that acts as a type of “off switch” to keep the immune system in check.

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Biosimilar Drugs Biosimilars for Cancer Treatment

Details: Biosimilar drugs are medicines that are very similar in structure and function to other biologic drugs, such as targeted therapy or immunotherapy used to treat some diseases, including certain types of cancer. Learn more about them here.

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Drug Therapy for Multiple Myeloma

Details: The drugs used most often for treating bone problems in people with myeloma are the bisphosphonates pamidronate (Aredia) and zoledronic acid (Zometa) and the drug denosumab (Xgeva, Prolia). These drugs are given intravenously (IV or into a vein) or subcutaneously (under the skin).

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Targeted Therapies for Chronic Myeloid Leukemia

Details: All of these drugs can have serious interactions with some other drugs, over-the-counter supplements, and even certain foods (such as grapefruit and pomegranates). Be sure that your doctor always has an up-to-date list of everything you're taking, including over-the …

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Chemotherapy Safety

Details: drugs use a special type of pharmacy that must meet certain regulations. And nurses and others who give your chemo and help take care of you afterwards wear protective clothing, such as 2 pairs of special gloves and a gown, and sometimes goggles or a face shield. If you're getting IV chemo, there might be a disposable pad under the

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Chemotherapy for Small Cell Lung Cancer Lung Cancer Chemo

Details: Drugs can be used to help prevent or treat low blood cell counts (especially low white blood cell counts). Trilaciclib (Cosela) is one example, although other drugs known as growth factors can be used as well. Some drugs can have specific side effects. For example: Drugs such as cisplatin and carboplatin can damage nerve endings.

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Biosimilar Drugs Safety Are Biosimilars Safe for Cancer

Details: Biosimilar Drug Safety. A biosimilar drug is a type of biologic drug — a medicine made from a biological or natural source. A biosimilar drug is a safe and effective, high-quality treatment that is "highly similar with no meaningful clinical differences" to a …

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Stomach Cancer Targeted Therapy Targeted Drugs for

Details: Drugs that target the HER2 protein can often be helpful in treating these cancers. Trastuzumab (Herceptin, others) Trastuzumab is a monoclonal antibody, a man-made version of an immune system protein, which targets HER2. Adding trastuzumab to chemo can help some people with advanced, HER2-positive stomach cancer live longer than just chemo alone.

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Aromatase Inhibitors for Lowering Breast Cancer Risk

Details: These drugs can also cause muscle and joint pain. This side effect can be serious enough to cause some women to stop taking the drugs. Unlike tamoxifen and raloxifene, AIs tend to speed up bone thinning, which can lead to osteoporosis. People with osteoporosis are more likely to have broken bones. AIs may raise cholesterol. Women with pre

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Chemotherapy Chemo Treatment for Cancer

Details: Chemotherapy (chemo) is the use of medicines or drugs to treat cancer. The thought of having chemotherapy frightens many people. But knowing what chemotherapy is, how it works, and what to expect can often help calm your fears. It can also give you a …

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Non-small Cell Lung Cancer Targeted Drug Therapy Lung

Details: Targeted drugs work differently from standard chemotherapy (chemo) drugs. They sometimes work when chemo drugs don’t, and they often have different side effects. At this time, targeted drugs are most often used for advanced lung cancers, either along with chemo or by themselves. Drugs that target tumor blood vessel growth (angiogenesis)

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Colorectal Cancer Targeted Therapy Targeted Drugs for

Details: Drugs that stop VEGF from working can be used to treat some colon or rectal cancers. These include: Bevacizumab (Avastin) Ramucirumab (Cyramza) Ziv-aflibercept (Zaltrap) These drugs are given as infusions into your vein (IV) every 2 or 3 weeks, in most cases along with chemotherapy.

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Targeted Drug Therapy for Breast Cancer

Details: Drugs that block kinases are called kinase inhibitors. Lapatinib (Tykerb): This drug is a pill taken daily. Lapatinib is used to treat advanced breast cancer, typically along with the chemo drug capecitabine or with certain hormone therapy drugs. Neratinib (Nerlynx): This kinase inhibitor is a pill taken daily.

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Chemotherapy for Waldenstrom Macroglobulinemia

Details: Chemo drugs may be used alone or combined with other drugs, such as targeted drugs or immunotherapy drugs. (For a list of some common combinations used in WM, see When to Treat People With Waldenstrom Macroglobulinemia.) Chemo side effects. Chemo drugs attack cells that are dividing quickly, which is why they work against WM cells.

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Quit Tobacco Prescription Smoking Cessation Drugs

Details: Other drugs being studied to help people quit tobacco A plant-based drug called cytisine has shown promise in other countries and is now being studied in the United States. Naltrexone is a drug used to help those with alcohol and opioid abuse disorders.

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Cervical Cancer Targeted Therapy Targeted Drugs for

Details: Drugs that target blood vessel formation . Vascular endothelial growth factor (VEGF) is a protein that helps tumors form new blood vessels (a process known as angiogenesis) to get nutrients they need to grow. Some targeted drugs called angiogenesis inhibitors stop VEGF from working and block this new blood vessel growth.

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What Are Biosimilar Drugs

Details: What Are Biosimilar Drugs?€ A biosimilar drug, or biosimilar, is a medicine that is very close in structure and function to a biologic drug. A biologic drug, or biologic, is a drug made from proteins or pieces of proteins (either natural or artificial). Unlike other drugs, biologic drugs must be made in€a living system,

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Other Drugs Used to Treat Adrenal Cancer

Details: Drugs other than mitotane may be used to block hormones made by the cancer or to lower the effects of the hormones. Treatment with some of these drugs may need to be supervised by an endocrinologist (hormone doctor) because they affect several hormone systems and might make it necessary to replace other hormones.

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Targeted Therapy Drugs for Childhood Leukemia

Details: Drugs called differentiation agents can help the blasts mature (differentiate) into normal white blood cells. Two of these drugs can be used to treat APL: All-trans-retinoic acid (ATRA, tretinoin) Arsenic trioxide (ATO) ATRA is a form of vitamin A that is typically part of the initial treatment of APL. It is given either along with chemo or

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Chemotherapy for Non-Hodgkin Lymphoma in Children

Details: Drugs can be given to help prevent or reduce nausea and vomiting. Infections can be very serious in children getting chemo. Drugs known as growth factors can be given to keep the blood cell counts higher. Tumor lysis syndrome is a possible side effect of chemo in children who have large numbers of lymphoma cells in the body before treatment. It

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Targeted Therapy for Malignant Mesothelioma

Details: Drugs that target blood vessel formation (VEGF) Vascular endothelial growth factor (VEGF) is a protein that helps tumors form new blood vessels (a process known as angiogenesis) to get nutrients they need to grow. Bevacizumab (Avastin ®) is a drug that stops VEGF from working. It's been found to help people with pleural mesothelioma live

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Immunomodulators and Their Side Effects

Details: These drugs can also cause severe birth defects if taken during pregnancy. Bacillus Calmette-Guérin. Bacillus Calmette-Guérin (BCG) is a germ that doesn’t cause serious disease in humans, but it does infect human tissues and helps activate the immune system. This makes BCG useful as a form of cancer immunotherapy.

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2019 in Review: New Cancer Drug Approvals

Details: Chemotherapy is one of the most powerful tools we have to treat cancer, and research continues to find new chemotherapy drugs as well as new uses for existing ones. At the same time, newer types of drugs are being developed that work in different ways to attack cancer cells. These types of treatments include targeted therapy, which aims to more precisely identify and go after cancer cells

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Chemotherapy for Nasopharyngeal Cancer

Details: Chemotherapy (chemo) is the use of anti-cancer drugs to treat cancer. These drugs are most often given into a vein (IV) or by mouth. They enter the bloodstream and reach throughout the body, making this treatment useful for cancers that have spread beyond the head and neck. Chemo may be used in different situations to treat nasopharyngeal

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Non-small Cell Lung Cancer Chemotherapy Chemo Side Effects

Details: For example, drugs can be given to help prevent or reduce nausea and vomiting. Some drugs can have specific side effects. For example, drugs such as cisplatin, vinorelbine, docetaxel, or paclitaxel can cause nerve damage ( peripheral neuropathy ).

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Targeted Therapy Drugs for Bladder Cancer

Details: Drugs that target cells with FGFR gene changes (called FGFR inhibitors) can help treat some people with bladder cancer. Erdafitinib (Balversa) This FGFR inhibitor can be used to treat locally advanced or metastatic bladder cancer that has certain changes in the FGFR2 or FGFR3 gene, and that is still growing despite treatment with chemo.

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Chemotherapy for Acute Lymphocytic Leukemia (ALL)

Details: Chemotherapy (chemo) is the use of drugs to treat cancer. Chemo drugs travel through the bloodstream to reach cancer cells all over the body. This makes chemo useful for cancers such as leukemia that has spread throughout the body. Chemo is the main treatment for just about all …

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Chemotherapy for Rhabdomyosarcoma

Details: Chemo drugs used to treat rhabdomyosarcoma. Doctors give chemo in cycles, which is usually treatment on 1 or 2 days in a row, followed by days off to give the body time to recover. For RMS, chemo is typically given once a week for the first few months, and then less often. The total length of treatment usually ranges from 6 months to a year.

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Targeted Therapy for Prostate Cancer

Details: Targeted Therapy for Prostate Cancer. Targeted therapy is a type of cancer treatment that uses drugs to identify and attack cancer cells while doing little damage to normal cells. These therapies attack the cancer cells' inner workings − the programming that makes them different from normal, healthy cells. Each type of targeted therapy works

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Lung Cancer Treatment by Stage Treating SCLC by Stage

Details: The most common combination of chemo drugs is etoposide plus either cisplatin or carboplatin. The immunotherapy drugs atezolizumab (Tecentriq) or durvalumab (Imfinzi) can be used along with etoposide and a platinum drug (cisplatin or carboplatin) for initial treatment and can then be continued alone as maintenance therapy.

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Types and Phases of Clinical Trials What Are Clinical

Details: The drugs are available for doctors to prescribe for patients, but phase IV studies might still be needed to answer important questions. These studies may involve thousands of people. This is often the safest type of clinical trial because the treatment has already been studied a …

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Immunotherapy for Breast Cancer

Details: Autoimmune reactions: These drugs remove one of the safeguards on the body's immune system. Sometimes the immune system starts attacking other parts of the body, which can cause serious or even life-threatening problems in the lungs, intestines, liver, hormone-making glands, kidneys, or other organs.

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Immunotherapy for Small Cell Lung Cancer SCLC Immunotherapy

Details: These drugs are given as an intravenous (IV) infusion, typically every 2, 3 or 4 weeks. Possible side effects of immunotherapy for SCLC. Side effects of these drugs can include fatigue, cough, nausea, skin rash, decreased appetite, constipation, joint pain, and …

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