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Drug Abuse Epilepsy Foundation

Details: The effects and risks of so-called recreational drugs vary greatly. They may directly affect the brain and seizures or interact with seizure medications. The effects will vary for different drugs and from one person to the next. Cocaine All forms of cocaine use can cause seizures within seconds, minutes, or hours after it is taken. Seizures caused by cocaine are uniquely …

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Seizure Medications List Epilepsy Foundation

Details: Each medicine tends to work better with certain kinds of seizures than for others. If one treatment fails, another may be work better. Select a Medication Brivaracetam Cannabidiol oral solution Carbamazepine Carbamazepine-XR Cenobamate Clobazam Clonazepam Diazepam Nasal Diazepam Rectal Divalproex Sodium Divalproex Sodium-ER Eslicarbazepine

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Alcohol and Drugs Epilepsy Foundation

Details: When you use alcohol or illegal drugs, trouble is not far behind. Risky decisions often put teens who use alcohol or other drugs in particularly dangerous places, such as behind the wheel of a motor vehicle. Teens often don't understand the potential dangers of drugs. If you have grown up in a home where alcohol and drugs were never abused, you most likely have no idea what

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Drugs and Alcohol Epilepsy Foundation

Details: When teens use alcohol or illegal drugs, trouble is not far behind. Their immaturity and willingness to take chances often put teens who use alcohol or other drugs in particularly dangerous places, such as behind the wheel of a motor vehicle. Few teens understand the potential dangers of drugs. Those who have grown up in homes where alcohol and drugs

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Summary of Antiepileptic Drugs Epilepsy Foundation

Details: Epilepsy.com has a great section on antiepileptic drugs (AEDs), but I often have been asked for a brief summary document that pulls the information into one package. This summary represents the opinion of the author, Dr. Robert Fisher, who is an epilepsy specialist, and it is not necessarily the official drug description that can be found in the package insert.

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Antimicrobial Drugs and Immunosuppression Epilepsy

Details: Antiviral drugs (e.g., acyclovir, ganciclovir) are used to treat encephalitis, which in itself causes seizures. Dideoxyiodinase and zidovudine, standard treatments for patients infected with human immunodeficiency virus (HIV), are said to increase seizure risk, 20 but it is difficult to exclude other factors, including unrecognized HIV

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Effects Of Epilepsy Medications Epilepsy Foundation

Details: Because most drugs are processed through the liver, there is an increased possibility for drug interactions. Some antiseizure drugs are not metabolized by the liver and these agents may lead to fewer drug interactions. One of the biggest problems …

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Antipsychotics and Seizures Epilepsy Foundation

Details: The absolute number of seizures reported with antipsychotic drugs is less than with antidepressants, but this may reflect the smaller number of people using antipsychotics, rather than a difference in the epileptogenic potential of this class of drugs.42 The incidence of psychosis in epileptic populations varies from 0.6% to 7.0% in general clinics and up to 27% in …

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Antidepressants Epilepsy Foundation

Details: By analyzing which transmitter systems are shared by proconvulsant drugs like local anesthetics, cocaine, phenothiazines, and tricyclic antidepressants, and then eliminating those with unique properties, Dailey and Naritoku concluded that it is the antihistaminic, antimuscarinic, and local anesthetic properties of antidepressants that are most

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Using Rescue Medications Epilepsy Foundation

Details: The names of benzodiazepines that are most commonly used as rescue medications include: diazepam (Valium®), lorazepam (Ativan®), and midazolam (Versed®). The availability of these medicines in different forms and how they are used may vary from country to country. In the United States, only rectal diazepam gel, commonly known by the brand

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Medications in Children Epilepsy Foundation

Details: Teens should also understand possible drug interactions with their seizure medication, particularly the impact of oral contraceptive pills, alcohol and other drugs. This is a conversation they should have with their health care provider.

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Drug Interactions Epilepsy Foundation

Details: Yes. Most seizure medicines (also known as antiepileptic drugs or AEDs) interact with each other and with other medicines. Such interactions are common and can be dangerous. The effects of interactions between two medications vary. Some seizure medicines can lower or raise the levels of other types of medicines in your blood.

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Over-the-Counter Medications as a Seizure Trigger

Details: Donate to Support Our Mission. Do over-the-counter (OTC) drugs affect seizures? A few medicines that you can get without a prescription (called over-the-counter or OTC medicines) can potentially increase seizures in people with epilepsy. They could even trigger a …

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Seizure Medications and Pregnancy Epilepsy Foundation

Details: There is limited information available on new anti-epileptic drugs and only slightly more on the classic anti-epileptic drugs. Given available information, it is recommended that the most effective drug with the fewest side effects be used. Most of the seizure medications can be used safely, though some carry increased specific risks.

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Seizures from Opioids and CNS Depressants Epilepsy

Details: Drugs and drug interactions may exacerbate epilepsy and contribute to intractability. Patients with epilepsy who require antiepileptic drugs (AEDs) must be warned of possible adverse interactions from drugs used for other illnesses, whether over-the-counter nostrums taken for common ailments or treatments prescribed by a physician for serious

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Amphetamines Epilepsy Foundation

Details: Amphetamines rarely cause seizures when used in therapeutic doses for treatment of attention deficit hyperactivity disorder, even in children with epilepsy. One patient with no previous history of seizures had a convulsion 3 hours after using 20 mg of methylphenidate to improve his concentration during college examinations (personal experience).

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Which are Better: Older or Newer Antiepileptic Medications

Details: The older drugs, as a rule, tend to require more monitoring of liver functions, blood counts and other types of blood tests, which definitely puts the newer drugs at an advantage. Another issue with the older drugs is that they are all known to have the potential to cause birth defects.

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Levetiracetam Epilepsy Foundation

Details: Levetiracetam (lev-eh-teer-ASS-eh-tam) is the generic name (non-brand name) for the drug called Keppra (KEP-ruh). Keppra is a widely used seizure medicine from UCB. Keppra is available in many countries, but the name or look may be different.

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Cenobamate Epilepsy Foundation

Details: Withdrawal of Antiepileptic drugs: Cenobamate like all other antiepileptic drugs should be withdrawn gradually because it can potentially increase the frequency of seizure occurrence and status epilepticus. Immediate withdrawal can be done if …

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2022 Epilepsy Pipeline Conference Epilepsy Foundation

Details: 2022 Epilepsy Pipeline Conference June 5-6, 2022. Attend in-person or virtual. Register Now. Early bird prices extended to MARCH 15, 2022. This premiere event is held every two years to bring together decision-makers in the field of epilepsy treatment, therapeutic innovation, and product development.

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Anxiolytics and Hypnotics Epilepsy Foundation

Details: All benzodiazepines treat symptoms of anxiety, and some shorter-acting ones are useful hypnotic agents.66 Benzodiazepines, such as chlordiazepoxide, have long proved useful in treating delirium, especially when associated with alcohol withdrawal. Some patients with epilepsy experience an aura resembling a panic attack (predominantly anxiety and fear),60 and anxiety …

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Drug-Resistant Epilepsy Epilepsy Foundation

Details: Two drugs have more side effects than does one drug, and three drugs more than two. Patients taking polypharmacy may have so many side effects that it is often difficult for someone to tolerate a higher dose for any of their ASMs.

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OTC and Herbal Medicines Epilepsy Foundation

Details: Stimulants of all types are implicated in seizure induction, even in patients without a pre-existing seizure disorder. Pseudoephedrine, pheniramine, and other over-the-counter (OTC) antihistamines are associated with seizures, especially in overdose (Of 43 people attempting suicide with pheniramine, 13 experienced seizures.)81 Stimulants used for weight loss or …

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Most Antidepressant Drugs Are Safe for Patients with

Details: This review found that most antidepressant drugs at appropriate doses are safe for people with epilepsy. Information on four medications showed a higher risk of causing seizures: clomipramine, bupropion, amoxapine, and maprotiline. Other causes of depression and anxiety need to be evaluated before treating a person with an antidepressant.

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Clobazam Epilepsy Foundation

Details: Clobazam (KLOH-bah-zam) is the generic name of the brand-name drugs known as Onfi ® and Sympazan™ in the United States and Frisium (FRIH-zee-um) in some other countries. The name or look of the medicine may be different in generic forms of clobazam.

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Seizures, Medications and Pregnancy Epilepsy Foundation

Details: Developmental effects of anti-epileptic drugs and the need for improved regulations. Neurology 2016; 86:297-306. Do different seizure drugs have different risks? Based on currently available data, valproic acid (Depakote) has the highest risk of causing both anatomical and cognitive/behavioral abnormalities in a developing child. Therefore, it

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Treating Epilepsy in Seniors Epilepsy Foundation

Details: Antiepileptic drugs (also called anticonvulsants) will usually prevent seizures or reduce their frequency once a certain level has. If the underlying cause of seizures is known, there may be ways to treat it directly -- with surgery or medication. However, if direct treatment isn't possible, then the doctor will usually prescribe

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North American AED Pregnancy Registry Epilepsy Foundation

Details: If you are pregnant, and take antiepileptic drugs (AEDs), please call toll free (888) 233-2334 to register with the AED Pregnancy Registry. This registry is run by researchers at Massachusetts General Hospital and Harvard Medical School. What is the purpose of the Registry? At present, we lack information about the relative safety of specific antiepileptic drugs (AEDs) during

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Seizure and Epilepsy Medicines Epilepsy Foundation

Details: Medicine is the most common way of treating epilepsy and is almost always the first treatment tried. There are many different medicines that can prevent or stop seizures. These are sometimes called anti-seizure medications (ASMs), anti-epileptic drugs (AEDs) or anti-seizure drugs. They will successfully control seizures for about 7 out of 10

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Psychedelics / Epilepsy Epilepsy Foundation

Details: Psychedelics / Epilepsy. I put my story here mostly to serve as a reference should anyone be inquiring about the use of Psychedelics and Epilepsy. It's a rather simple story, but I believe it's one that could be extremely informative to some people. I was a healthy 39-year-old male who battled a low lying depression for much of my adult life.

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Seizures Caused by Surgery and Anesthesia Epilepsy

Details: Seizures may occur in close relation to surgical procedures or use of anesthetic agents in several situations: Interruption of treatment with antiepileptic drugs (AEDs) may result from orders to be non per os before anesthesia. Short procedures may require delaying only a single dose, and this delay may still be within the drug's effective half-life. In such cases, a patient can be given one

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Alcohol Epilepsy Foundation

Details: Alcohol has been known to produce seizures since antiquity, but the relationship is complex. Seizures27 and status epilepticus87 have been reported in both acute intoxication and withdrawal. They also may be secondary to complications of alcohol abuse, such as subdural or parenchymal hemorrhage, stroke, or head trauma.27,88,89 Alcohol acts as a depressant at …

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Women Epilepsy Foundation

Details: Learn about unique issues for women with epilepsy like the impact of hormones on seizures, birth control, pregnancy, parenting, menopause, and bone health.

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Anti-Seizure Medications During Pregnancy Epilepsy

Details: Monitoring appears less important for drugs such as carbamazepine and valproic acid, where changes in drug levels are usually minor. Monitoring is more important for drugs with marked, but unpredictable, changes, such as lamotrigine, levetiracetam, oxcarbazepine, and possibly topiramate. Summary

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Metabolic Encephalopathy Epilepsy Foundation

Details: Anticonvulsant drugs alone are generally ineffective, and dose adjustments are needed if they are used. A metabolic encephalopathy should be suspected and appropriate screening tests ordered when seizures arise after procedures associated with significant fluid shifts, such as bladder lavage, hemodialysis, radiographic procedures using

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Physiology of Drug Clearance Epilepsy Foundation

Details: To understand the effects of renal impairment and hemodialysis on steady-state drug plasma concentration, it is first necessary to understand the normal physiology of renal clearance of drugs.29 Renal excretion is one route of drug elimination. Drugs also may be eliminated entirely by hepatic excretion or other nonrenal routes, or by a combination of renal and nonrenal routes.

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Phenytoin Epilepsy Foundation

Details: Phenytoin is the generic name of a widely used antiepileptic drug (AED). In the United States, phenytoin is known by the brand names Dilantin and Phenytek (an extended-release form). In the UK, the brand name is Epanutin. Sometimes the savings from using generic medications instead of brand-name products are large, but with other products the

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Seizure Complications of Antibacterial Treatment

Details: Incidence Most antibiotics are CNS-safe, and neurotoxicity associated with their administration is infrequent.31 There have been anecdotal reports of seizures complicating antibiotic use, however, and such associations are reported more often for certain drugs. Beta-lactams are the antibiotic class most commonly associated with adverse CNS events. The exact incidence of seizures …

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Diet, Drugs, sleep What is known to increase/decrease

Details: Re: Diet, Drugs, sleepWhat is known to affect seizures? Submitted by Gubs on Wed, 2010-03-24 11:43 Hi Tadzio, thank-you for your incredibly detailed response.

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Major Antimicrobial-Anticonvulsant Interactions Epilepsy

Details: Antimicrobial Anticonvulsant Antimicrobial Effect Anticonvulsant Effect Itraconazole Carbamazepine None ↓ level Phenytoin ↓ level ↑ level Fluconazole Phenytoin ↓ level ↑ level Ketoconazole Phenytoin ↓ level ↑ level Chloramphenicol Phenytoin None ↑ toxicity Clindamycin Diazepam None ↑ effect Doxycycline Phenobarbital ↓ absorption, ↓ serum terminal half-life ↑ level

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Eighth Eilat Conference on New Antiepileptic Drugs

Details: These new drugs represent the next generation of existing marketed drugs, and whether or not they will have advantages over their predecessors remains for clinical research to demonstrate. Day Three was a review of new studies of drugs that are already being used clinically. In addition, there was discussion of vagus nerve stimulation.

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Blood Testing Epilepsy Foundation

Details: The so-called therapeutic range of blood levels for seizure medications is the range of drug in the body where most patients have good seizure control and few or no side effects. The lower and upper limits of this range can vary between different laboratories and different drugs. When is the best time to test blood levels of a drug?

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Differentiating Nonepileptic Behavior Epilepsy Foundation

Details: If treatment is necessary, antidepressant or dopamine receptor–blocking drugs should be used, not AEDs. Using the lowest dosage that successfully controls tics is important, because the antidepressant used most commonly in this disorder, fluvoxamine, has been associated with seizures or EEG spikes in at least one patient. 38

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Aplastic Anemia Epilepsy Foundation

Details: Drugs can cause idiosyncratic bone marrow suppression or dose-related suppression. Idiosyncratic bone marrow suppression is a life-threatening event that is not related to dose or to the duration of administration and cannot be predicted by repeated blood draws.42–44 Patients with a history of serious drug reactions,

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Effects of AEDs on Sleep Epilepsy Foundation

Details: Another reason that patients with epilepsy are at risk for sleep disorders is that treatment with antiepileptic drugs (AEDs) may directly contribute to daytime sleepiness or insomnia, or may exacerbate underlying sleep disorders like obstructive sleep apnea. On the other hand, these drugs may also improve sleep organization. Studies of people taking AEDs have found that …

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AED Treatment Epilepsy Foundation

Details: Of patients with brain tumors Patients with cerebral neoplasms who develop epilepsy should be treated with antiepileptic drugs (AEDs), but there is no consensus in the literature about which AEDs are most effective. Most studies assessing the use of AEDs in these patients involve the older AEDs, including phenytoin, phenobarbital, carbamazepine, and valproic acid.

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Predicting Drug Resistance in Adult Patients with

Details: Most Antidepressant Drugs Are Safe for Patients with Epilepsy at Therapeutic Doses: A Review of the Evidence; Neurobehavioral Problems in Children with Early-onset Epilepsy: A Population-based Study; Parental Stress, Pediatric Quality of Life, and Behavior at Baseline and One-year Follow-up: Results from the FEBSTAT Study

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Tips for Day to Day Living Epilepsy Foundation

Details: Using either is a real risk, because drugs are against the law and using alcohol -- if you are a minor -- is also illegal. You could get caught. You don't want that kind of trouble. Besides, mixing street drugs with epilepsy meds is even riskier. Some illegal drugs -- cocaine, for example -- can cause seizures in people who don't even have

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Folate Deficiency Epilepsy Foundation

Details: Folate deficiency is one of the causes of macrocytic anemia. It does not cause seizures, although it may involve the central nervous system, producing neuropsychiatric complications.1 The association between folate deficiency and epilepsy involves common antiepileptic drugs (AEDs): AEDs can impair folate absorption. AEDs, including phenytoin, carbamazepine, and …

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