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Drug news and latest updates

Details: Drugs are usually distinguished from endogenous biochemicals by being introduced from outside the organism.[citation needed] For example, insulin is a hormone that is synthesized in the body; it

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We can expect more COVID drugs next year, but we've wasted

Details: Several COVID drugs are in the pipeline for 2022, some you can potentially take at home, others for use in hospital. It's taken almost two years of the pandemic to get here. However, as we argue

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Antihypertensive drugs are effective in hereditary

Details: Antihypertensive drugs are effective in hereditary cerebral small vessel disease. Therapeutic effect of candesartan on cerebral arteriopathy via inhibition of matrisome protein accumulation

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Two COVID-19 pills could change the course of the pandemic

Details: Both drugs have the potential to keep people out of the hospital and help them avoid serious illness. The treatments could also help reduce the number of days that a person has COVID-19 symptoms

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A target for potential cancer drugs may, in fact, worsen

Details: A target for potential cancer drugs may, in fact, worsen disease. In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name

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Illicit drugs, high alcohol consumption both linked to

Details: Illicit drugs, high alcohol consumption both linked to first-time, irregular heart rhythm. A 12 lead ECG showing atrial fibrillation at approximately 150 beats per minute. Credit: James Heilman

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Police scare campaigns won't stop people from using drugs

Details: Police scare campaigns won't stop people from using drugs, but will increase stigma. As part of a Halloween-inspired campaign, the Australian Federal Police has released a series of ill-advised

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New target identified for rapid antidepressant drugs

Details: Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects. This represents a new target for drug development that could fill a major gap in care

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Deaths with drugs as contributing factor are rising

Details: "Drugs as a contributing cause increases the death toll from drugs nearly 8% beyond overdose deaths alone," Vuolo said.. The most striking statistics were the changes in the proportion of deaths

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Scientists identify 160 new drugs that could be repurposed

Details: Cambridge scientists have identified 200 approved drugs predicted to work against COVID-19—of which only 40 are currently being tested in COVID-19 clinical trials.

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New potential drugs for muscle dystrophy found using stem

Details: New potential drugs for muscle dystrophy found using stem cells. by Kyoto University. Figure 1. Store-operated Ca 2+ channels (SOCs) regulate Ca 2+ overload in dystrophic myotubes using induced

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Diet trumps drugs for anti aging and good metabolic health

Details: Diet trumps drugs for anti aging and good metabolic health. A study comparing the impact of diet versus drugs on the inner workings of cells has found nutrition has a much stronger impact. The pre

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Decriminalizing drug use is necessary, but won't end

Details: Negative views towards drugs and people who use them is a major factor in the overdose crisis. By reshaping the way our family, friends and the medical profession think about drugs, drug use can

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How adolescents used drugs during the COVID-19 pandemic

Details: However, one change was a decreased use of alcohol, but an increased use of nicotine and misuse of prescription drugs. The findings, publishing in the August 24, 2021 issue of the

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Bench-to-bedside drug design could lead to new Alzheimer's

Details: However, there are drugs that work to recover memory loss and improve cognitive function in early dementia, but these drugs are often not very effective, and are associated with side effects that

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The people most at risk of HIV in Kenya aren't using

Details: The people most at risk of HIV in Kenya aren't using preventive drugs. There has been a gradual decline of new HIV cases overall in Kenya—from a high of 230,000 new infections in 1992 to 33,000

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Merck v Pfizer: How the two new COVID antiviral drugs work

Details: Merck v Pfizer: How the two new COVID antiviral drugs work and will be used. We've waited 20 months for a medicine to blunt the coronavirus, and now two have appeared. Earlier this month, the UK

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Many people with high blood pressure may take a drug that

Details: "The risk of [drugs] raising blood pressure may be simply overlooked, particularly for patients using these additional medications for many years," said study author Dr. Timothy Anderson. He is a

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Light-activated drugs provide localized medicine without

Details: Light-activated drugs provide localized medicine without side effects. Team led by Professor Francisco Ciruela. Credit: UB-IDIBELL-UBNeuro. Photopharmacology is an emerging area of science based

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Supply chain issues bring shortages of drugs, devices to U

Details: Supply chain issues bring shortages of drugs, devices to U.S. hospitals. by Dennis Thompson. (HealthDay)—The word went out late last month throughout Utah—if you've got a …

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Do some diabetes drugs reduce the risk of Alzheimer's

Details: People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer's disease, when compared to both people with type 2 diabetes not taking

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Why prescription drugs can work differently for different

Details: Some drugs block the active site of the liver enzyme cytochrome P450 so it can't be reused, preventing other drugs from binding to it and getting metabolized. As drug concentrations rise, so does

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Drugs designed for prostate cancer show promise for

Details: The new study from researchers at the Perelman School of Medicine at the University of Pennsylvania uses melanoma models in mice to show that drugs that target androgen receptors (AR) in prostate

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New experimental drug cagrilintide (AM833), when combined

Details: Novo Nordisk A/S is the manufacturer of both drugs in this study. An early study of a new experimental drug to treat obesity known as cagrilintide shows that, when combined with semaglutide 2.4 mg

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Drugs that mimic effects of cigarette smoke reduce SARS

Details: Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that

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Recreational drugs news and latest updates

Details: Sex, drugs, and genes: Moral attitudes share a genetic basis. Few hallmarks of the 1960s counterculture stand out like sex, drugs, and rock-n-roll—elements of a "lifestyle" that Life magazine

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One hundred fifty five drugs and 79 vaccines under

Details: A total of 155 drugs and 79 vaccines are currently being developed worldwide to combat COVID-19. The Austrian Institute for Health Technology Assessment (AIHTA) has compiled these astonishing

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Two anti-inflammatory drugs found that inhibit the

Details: Finding drugs that can inhibit the infection caused by SARS-CoV-2 is an essential step to finding the vaccine that can definitively bring the spread of the virus to an end.

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Two new studies examine rising cancer drug spending in the US

Details: As cancer drug spending grows, so do doubts over the evidence supporting the drugs' approvals and efficacy. Two new studies led by the Harvard Pilgrim Health Care Institute examine the use of and

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Mechanism behind ineffective psoriasis drugs identified

Details: Mechanism behind ineffective psoriasis drugs identified. by University of Zurich. In inflamed skin keratinocytes with the receptor for interleukin-12 (left) divide less than keratinocytes without

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Microrobots designed to deliver drugs to diseased cells

Details: Uptake of conventional drugs by diffusion is inefficient, but having microrobots transport a drug specifically to the site of a stomach tumor and then deliver it there might make the drug's uptake

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New combination of old drugs improves survival in patients

Details: A novel combination of well-known drugs prolongs survival in patients with hormone/castration-sensitive prostate cancer, according to late breaking research presented at the ESMO Congress 2021.

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Some FDA-approved drugs could be repurposed to treat

Details: Kadler adds, "We identify drugs that stop replication of the SARS-CoV-2 virus (which is the cause of COVID-19) in human cells in culture. The drugs include ebastine, which is approved by the FDA

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Potential new drug for incurable vascular dementia

Details: Drugs to prevent stroke and dementia show promise in early trial. Apr 25, 2019. Recommended for you. Combination therapy reduces toxic aggregates in Parkinson's disease. Nov 24, 2021.

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Could oral antiviral pills be a game-changer for COVID-19

Details: Two new antiviral drugs could soon be the first effective oral treatments for COVID-19 to help keep people out of the hospital. An advisory committee to the Food and Drug Administration plans to

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Common medications accumulate in gut bacteria, which may

Details: The drugs were chosen to represent a range of different types of common drugs, including antidepressant medications, which are known to affect individuals dissimilarly and cause side effects such

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Sex, drugs, and genes: Moral attitudes share a genetic basis

Details: Sex, drugs, and genes: Moral attitudes share a genetic basis. Few hallmarks of the 1960s counterculture stand out like sex, drugs, and rock-n-roll—elements of a "lifestyle" that Life magazine

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Novel computational pipeline could help repurpose cancer

Details: The drugs currently available for PH dilate or relax these blood vessels, which can give relief from symptoms and prolong the time it takes for the disease to progress, but they're not curative.

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Immunosuppressants linked to severe reactions in people

Details: The drugs are prescribed for a variety of conditions, and two of the medications have been given for severe COVID-19, raising concern that a large number of patients are at risk.

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Can I still use prescription drugs after they expire

Details: The study showed that 90 per cent of more than 100 drugs, both prescription and over-the-counter, were fine to use well after expiry dates had passed, and in some cases more than 15 years after

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Trial results of new drug for generalized myasthenia gravis

Details: Trial results of new drug for generalized myasthenia gravis. Argenx, a Belgium pharmaceutical company, recently announced that The Lancet Neurology has published pivotal trial results from the

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Cancer costs U.S. more than $156 billion, with drugs a

Details: Cancer costs U.S. more than $156 billion, with drugs a leading expense. Care for the 15 most prevalent types of cancer in the U.S. cost approximately $156.2 billion in 2018, according to a team of

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Dopamine, drugs, and depression

Details: Dopamine, drugs, and depression. The neurotransmitter dopamine plays a major role in mental illnesses like substance abuse disorders and depressive disorders, as well as a more general role in

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New drugs are improving survival times for patients with

Details: Survival times for a highly aggressive type of blood cancer have nearly doubled over the last decade due to the introduction of new targeted drugs, a Yorkshire study has shown.

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New drug shows promise in treating early-stage breast cancer

Details: New drug shows promise in treating early-stage breast cancer. Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth

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Immunology researcher probes regulatory T-cell biology to

Details: Immunology researcher probes regulatory T-cell biology to develop living drugs. Dr. Leonardo Ferreira’s research involves optimizing chimeric antigen receptors on T-cells to better direct the T

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Team achieves cancer therapy breakthrough in vitro using

Details: Team achieves cancer therapy breakthrough in vitro using 'self-assembled' drugs. by University of Huddersfield. Two different compounds were generated using zinc (left) and manganese (right

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