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Drugs and Lactation Database (LactMed)

Details: LactMed, the Drugs and Lactation Database, contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant.

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NCI Investigational Drugs

Details: NCI Investigational Drugs - PubChem data source information. Find all the data submitted to PubChem by NCI Investigational Drugs.

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NCI Cancer Drugs

Details: The collection of NCI Cancer Drugs has over 200 cancer drug information summaries from NCI. The summaries provide consumer-friendly information about cancer drugs and …

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N,N-Dimethyltryptamine C12H16N2

Details: Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.

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Benzoylecgonine C16H19NO4

Details: Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain

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Atropine C17H23NO3

Details: Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands

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Risdiplam C22H23N7O

Details: Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor [nusinersen], the biggest difference being their route of administration: nusinersen requires intrathecal administration

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Succinylcholine C14H30N2O4+2

Details: The drugs should be used with extreme caution, if at all, in patients with myasthenia gravis. Other conditions that are associated with increased response to the neuromuscular blocking agents are the myasthenic syndrome associated with lung cancer, dehydration, thyroid disorder, collagen diseases, porphyria, and familial periodic paralysis.

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› Url: https://pubchem.ncbi.nlm.nih.gov/compound/succinylcholine Go Now

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PubChem Structure Search

Details: Try the new PubChem Search. Georganics Active Biopharma AbaChemScene Life Technologies, Applied Biosystems, Ambion Bhaskar Lab, Department of Zoology, Sri Venkateswara University Meiler Lab, Vanderbilt University Anward Anitha, Department of Bioinformatics, Karpagam University Chembase.cn InfectX Consortium NextMove Software 4C Pharma

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Heroin C21H23NO5

Details: Drugs visualized in this way are identified on the basis of (a) reference values (ratio between the distance the mobile phase moves up the plate and the distance the compound moves from the point of application), (b) metabolic patterns (parent drug and characteristic metabolite), and (c) functional group analysis (chemical characteristics as

› Verified 8 days ago

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Phenothiazine C12H9NS

Details: Phenothiazine is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.In addition, these agents have peripherally or centrally antagonistic activity against alpha adrenergic, serotonergic

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Folfirinox Regimen C65H76FN15O19Pt

Details: Drugs in the FOLFIRINOX combination: FOL = Leucovorin Calcium ( Folinic Acid) ; F = Fluorouracil ; IRIN = Irinotecan Hydrochloride ; OX = Oxaliplatin. FOLFIRINOX is used to treat: • Pancreatic cancer that has metastasized (spread to other parts of the body). NCI Cancer Drugs.

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Methicillin C17H20N2O6S

Details: Methicillin is a penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a methicillin (1-).

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Piperidine C5H11N

Details: Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen.It is a metabolite of cadaverine, a polyamine found in the human intestine.It has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a …

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Epinephrine C9H13NO3

Details: Epinephrine is the drug of choice in the emergency treatment of severe acute anaphylactic reactions including anaphylactic shock. Symptoms such as urticaria, pruritus, angioedema, and swelling of the lips, eyelids, and tongue which may result from reactions to drugs, sera, insect stings, food, or other allergens may be relieved by epinephrine.

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Amphetamine C9H13N

Details: Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted.

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Scopolamine C17H21NO4

Details: Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands

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Penicillin g C16H18N2O4S

Details: Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins.Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic

› Verified 4 days ago

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DRD4 (human) Gene Target

Details: DRD4 - dopamine receptor D4 (human) This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including

› Verified 8 days ago

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Carbovir C11H13N5O2

Details: Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS. (See all …

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Captopril C9H15NO3S

Details: Captopril is a sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits angiotensin converting enzyme (ACE), thereby decreasing levels of angiotensin II, increasing plasma renin activity, and decreasing aldosterone secretion. This agent may also inhibit tumor angiogenesis by inhibiting endothelial cell matrix

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Paritaprevir C40H43N7O7S

Details: Paritaprevir is a Hepatitis C Virus NS3/4A Protease Inhibitor. The mechanism of action of paritaprevir is as a HCV NS3/4A Protease Inhibitor, and Organic Anion Transporting Polypeptide 1B1 Inhibitor, and Organic Anion Transporting Polypeptide 1B3 Inhibitor, and Breast Cancer Resistance Protein Inhibitor, and UGT1A1 Inhibitor, and P-Glycoprotein Inhibitor.

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Methcathinone C10H13NO

Details: Methcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology). 2-methylamino-1-phenylpropan-1-one is an aromatic ketone that is propiophenone in which the hydrogen alpha- to the keto group has been replaced by a methylamino group. It is an aromatic ketone and a secondary amino compound.

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Salbutamol C13H21NO3

Details: Salbutamol | C13H21NO3 | CID 2083 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety

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Phencyclidine C17H25N

Details: Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.

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Methamphetamine C10H15N

Details: Methamphetamine is a member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. It has a role as a neurotoxin, a psychotropic drug, a central nervous system stimulant, a xenobiotic and an environmental contaminant. It is a member of amphetamines and a secondary amine.

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Mephedrone C11H15NO

Details: Mephedrone is an aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes. It has a role as a xenobiotic and an environmental contaminant.

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Humalog C257H383N65O77S6

Details: Insulin Lispro is a recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid proline at B-28 and the amino acid lysine at B-29 are reversed, resulting in the rapid dissolution of this insulin to a monomer that is absorbed rapidly after subcutaneous administration. Lispro insulin is equipotent to human insulin on a

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Metoclopramide C14H22ClN3O2

Details: Metoclopramide is a member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.It has a role as an antiemetic, a dopaminergic antagonist, a gastrointestinal drug, a xenobiotic and an environmental contaminant.

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Maribavir C15H19Cl2N3O4

Details: Maribavir is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of viral UL97 kinase, which is involved in viral nuclear maturation events, such as viral DNA assembly and movement of viral capsids from the nucleus of infected cells. Maribavir has activity against strains of CMV that are resistant to standard

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Marizomib C15H20ClNO4

Details: Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity.

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Oclacitinib C15H23N5O2S

Details: Veterinary drugs -> Apoquel -> EMA Drug Category. European Medicines Agency (EMA) Agents for dermatitis, excluding corticosteroids -> Veterinary pharmacotherapeutic group. European Medicines Agency (EMA) Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients. FDA Drugs. 9 Literature. Help.

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Amrinone C10H9N3O

Details: Amrinone is a 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure. It has a role as an EC …

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Gadodiamide C16H28GdN5O9

Details: New Window. Omniscan (gadodiamide) Injection is the formulation of the gadolinium complex of diethylenetriamine pentaacetic acid bismethylamide, and is an injectable, nonionic extracellular enhancing agent for magnetic resonance imaging. Omniscan is administered by intravenous injection.

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Olaparib C24H23FN4O3

Details: Olaparib is a member of the class of N-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of N-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer.It has a role as an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis

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(r)-Omeprazole C17H19N3O3S

Details: Omeprazole and esomeprazole therapy are both associated with a low rate of transient and asymptomatic serum aminotransferase elevations and are rare causes of clinically apparent liver injury. (R)- omeprazole is a 5-methoxy-2- { [ (4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has R configuration at the sulfur atom.

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Methotrexate C20H22N8O5

Details: Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of

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Cosmetics, quasi-drugs, pharmaceuticals, food

Details: 1 Abstract. (57) [Summary] (Modified) [Problem] To provide cosmetics, quasi-drugs and the like containing a substance having a tyrosinase inhibitory effect and effective for improving whitening and blemishes. SOLUTION: The chemical formula 1 (where n = 1 to 20, R 1 to R 1) Reference numeral 8 denotes cosmetics, quasi-drugs, pharmaceuticals, and

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Gamithromycin C40H76N2O12

Details: Veterinary drugs -> Zactran-> EMA Drug Category. European Medicines Agency (EMA) Antibacterials for systemic use -> Veterinary pharmacotherapeutic group. European Medicines Agency (EMA) Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients. FDA Drugs. 9 Safety and Hazards. Help. New Window.

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Barbiturate C4H3N2O3-

Details: Barbiturate | C4H3N2O3- | CID 3262018 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities

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Pilocarpine C11H16N2O2

Details: Pilocarpine is a natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract.

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Bupropion hydrochloride C13H19Cl2NO

Details: A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake. (See all compounds classified as …

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Administration of anti-inflammatory drugs to the central

Details: During at least part of the time that a nonsteroidal anti-inflammatory drug (NSAID) is present in the blood, from the systemic blood circulation of the subject across the blood brain barrier (BBB) to at least part of the central nervous system (CNS) At least one of the subject's CNS through the systemic blood circulation of the subject, comprising a stimulator (4) and an electrode (7

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4'-Fluorococaine C17H20FNO4

Details: 4'-Fluorococaine | C17H20FNO4 | CID 14808821 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities

› Verified 8 days ago

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Vortioxetine hydrobromide C18H23BrN2S

Details: Vortioxetine hydrobromide is a hydrobromide obtained by combining vortioxetine with one molar equivalent of hydrobromic acid. Used for treatment of major depressive disorder. It has a role as an antidepressant, an anxiolytic drug, a serotonergic antagonist and a serotonergic agonist. It contains a vortioxetine (1+).

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