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Pharmaceuticals News -- ScienceDaily

Details: Nov. 16, 2021 — The most common pharmaceuticals on the market are made by chaining together rings of molecules to create the drugs that treat conditions including pain, depression and leukemia

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Psychedelic Drugs News -- ScienceDaily

Details: Medical research on LSD and related psychedelic drugs. From mystical experiences induced by "sacred mushrooms" to the potential use of LSD to treat alcoholism, read it all here.

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Researchers train computers to predict the next designer drugs

Details: "The fact that we can predict what designer drugs are likely to emerge on the market before they actually appear is a bit like the 2002 sci-fi movie, Minority Report, where foreknowledge about

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Study identifies possible COVID-19 drugs -- including

Details: Of the nine drugs found to reduce SARS-CoV-2 replication in respiratory cells, three already have FDA approval: the transplant-rejection drug cyclosporine, the cancer drug dacomitinib, and the

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How adolescents used drugs during the COVID-19 pandemic

Details: Among adolescents ages 10 to 14 in the U.S, the overall rate of drug use remained relatively stable in the first six months of the COVID-19 pandemic. However, one change was a decreased use of

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A tool to interrogate a new class of drugs -- ScienceDaily

Details: Reactive electrophilic drugs like Tecfidera, approved for the treatment of relapsing multiple sclerosis, show a lot of potential but are also mystery. Scientists have now used an innovative

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Many Common Drugs Promote Tooth Decay -- ScienceDaily

Details: Many Common Drugs Promote Tooth Decay. For teeth constantly on the mend from the effects of acid-producing bacteria that set up housekeeping in our mouths, saliva is a fabulous fluid. Saliva

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Smoking, Drinking, Drugs: The Younger They Start, The

Details: Smoking, Drinking, Drugs: The Younger They Start, The Harder It Is To Quit. Date: November 19, 1997. Source: Center For The Advancement Of Health. Summary: Young people who experiment with tobacco

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Biopharmaceutical

Details: Biopharmaceuticals are medical drugs produced using biotechnology. They are proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) used for therapeutic or in vivo

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A better-fitting molecular ‘belt’ for making new drugs

Details: The most common pharmaceuticals on the market are made by chaining together rings of molecules to create the drugs that treat conditions including pain, depression and leukemia. But creating those

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Heartburn drugs may have unexpected benefits on gum

Details: Heartburn drugs may have unexpected benefits on gum disease. New research found that patients who used drugs prescribed to treat heartburn, acid reflux and ulcers were more likely to have smaller

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Nanomedicine: Drugs can be made 'smarter' -- ScienceDaily

Details: A new method has been developed to make drugs 'smarter' using nanotechnology so pharmacologists can tailor their drugs to more accurately target an area on the body, such as a cancer tumor.

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Do some diabetes drugs reduce the risk of Alzheimer’s

Details: People taking certain drugs to lower blood sugar for type 2 diabetes had less amyloid in the brain, a biomarker of Alzheimer's disease, when compared to both people with type 2 diabetes not taking

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Diet trumps drugs for anti-aging and good metabolic health

Details: The study was designed to examine the impact of three anti-ageing drugs on the liver, which is a key organ in the regulation of metabolism. A key strength of the study was the use of the geometric

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Toxic DNA buildup in eyes may drive blinding macular

Details: The researchers' new work in lab mice suggests these drugs, or safer derivatives known as Kamuvudines, could block the harmful inflammation and protect against retinal cell death.

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Drugs used by some Type 2 diabetics may lessen risk for

Details: The researchers also studied two other drugs that are used as treatments for Type 2 diabetes and are known to have anti-inflammatory effects -- dipeptidyl peptidase-4 (DPP-4) inhibitors and

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Families of drugs developed from bacteria, fungi, snails

Details: Nature-derived drugs not in every species. The conventional view about nature-derived drugs is that as every nature species produces biologically active molecules, one can find drugs from almost

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Nasal drugs show promise for slowing Parkinson’s disease

Details: The drugs, which were delivered through the nose, were found to slow inflammation in the brain and stop the spread of alpha-synuclein in mice with Parkinson's disease. The treatments also improved

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Mechanism behind ineffective psoriasis drugs identified

Details: Mechanism behind ineffective psoriasis drugs identified. Interleukin-12 -- a messenger molecule of immune cells -- was long considered to trigger the development of psoriasis. Now, researchers

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Most cases of never-smokers’ lung cancer treatable with

Details: The new analysis suggests that 78% to 92% of lung cancers in patients who have never smoked can be treated with precision drugs already approved by the Food and Drug Administration to target

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Novel computational pipeline could help repurpose cancer

Details: The drugs currently available for PH dilate or relax these blood vessels, which can give relief from symptoms and prolong the time it takes for the disease to progress, but they're not curative.

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Stem cell drugs surprise researchers: Could lead to better

Details: The drugs tested by the researchers mobilize stem cells by acting as CXCR4 receptor antagonists. This means that they inhibit or reduce activity of the receptor. Several drugs target this receptor

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Using drugs for different diseases than initially intended

Details: Using drugs for different diseases than initially intended for. One drug, one disease. This is how we traditionally think about pharmaceutical drugs, but many of them are actually effective for

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Study reveals existing drugs that kill SARS-CoV2 in cells

Details: Study reveals existing drugs that kill SARS-CoV2 in cells. A new study reveals several drug contenders already in use for other purposes that have been shown to block or reduce SARS-CoV2 infection

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Nerves may be key to blocking abnormal bone growth in

Details: The findings, published in Nature Communications, suggest that drugs currently being tested in clinical trials to inhibit this molecule for pain relief could also protect against this challenging

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Drug cocktail reduces aging-associated disc degeneration

Details: Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nature Communications, 2021; …

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Old drugs, new tricks: Medications approved for other uses

Details: A number of drugs already approved to treat parasitic infections, cancers, infertility and other conditions also show promise as antibiotic agents against staph and tuberculosis infections

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Stents inspired by paper-cutting art can deliver drugs to

Details: Stents could offer a way to deliver drugs to a targeted portion of the digestive tract, but inserting any kind of stent into the GI tract can be tricky because digested food is continuously moving

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Understanding The Body's Rejection Of Drugs -- ScienceDaily

Details: Drugs have got to have a molecule in the body to target. But a drug has to cross all the body tissues prior to reaching its target and this is incredibly tricky and very difficult from the drug

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'Self-medication': Why doctors abuse prescription drugs

Details: Doctors who abuse prescription drugs often do so for "self-medication" -- whether for physical or emotional pain or stress relief, reports a study in the October Journal of Addiction Medicine, the

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Specific molecular mechanism that controls the transition

Details: A new study reveals the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines.

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Unique underpinnings revealed for stomach’s acid pump: New

Details: Drugs that block the enzyme's activity could therefore reduce acidification and ease ulcer symptoms. To design more effective drugs, scientists need to know how the protein works. In this study

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Many patients abusing drugs, alcohol are self-medicating

Details: If drugs are being used to self-medicate pain, patients may be reluctant to decrease, stop, or remain abstinent if their pain symptoms are not adequately managed with other treatments including

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Researcher discovers new 'anti-pathogenic' drugs to treat

Details: A researcher has identified new anti-pathogenic drugs that, without killing the bacteria, render methicillin resistant Staphylococcus aureus harmless by preventing the production of toxins that

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Many pregnant teens use alcohol and drugs, study finds

Details: Many teenagers, especially younger teens, may not be getting the message about the risks of using alcohol and other drugs during pregnancy, researchers say -- but that having involved parents and

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Strong Pain-killing Drugs Without The Addiction

Details: Dec. 5, 2017 — Opioid drugs are the most widely prescribed and effective type of pain medication. But they are highly addictive and have some unpleasant and potentially deadly side effects.

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The hunt for drugs to neutralize critical enzymes

Details: The new Bath paper explores all known strategies used to design or discover such drugs, including methods adopted to measure racemase function and by extension drug effectiveness.

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Antidepressants inhibit cancer growth in mice -- ScienceDaily

Details: "Drugs that are already approved for clinical use as antidepressants could help improve treatment of hitherto incurable pancreatic and colorectal cancers," says Pierre-Alain Clavien, director of

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Nearly 7 in 10 Americans are on prescription drugs

Details: Drugs were prescribed to both men and women across all age groups, except high blood pressure drugs, which were seldom used before age 30. Overall, …

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'Ego-dissolving' psychedelic drugs could assist with

Details: The altered state of consciousness and temporary lack of ego that results from using psychedelic drugs could help some mental health patients recover from their symptoms, according to academics.

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Adolescent exposure to drugs, alcohol fuels use in

Details: Adolescent exposure to drugs, alcohol fuels use in adulthood. Date: July 29, 2016. Source: Michigan State University. Summary: Teenagers who have easy access to drugs and alcohol in the home are

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Memory Enhancement Drugs Show Promise But Face Growing

Details: Memory Enhancement Drugs Show Promise But Face Growing Scrutiny. In our aging society, with an increased urgency to develop new compounds that target serious illnesses like Alzheimer's and

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Supercomputers assist in search for new, better cancer drugs

Details: Finding new drugs that can more effectively kill cancer cells or disrupt the growth of tumors is one way to improve survival rates for ailing patients. Researchers are using supercomputers to find

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Knock-Out Drugs: Narrow Window For Detection -- ScienceDaily

Details: Many substances can be used as knock-out drugs, for example alcohol and liquid ecstasy. However, the most important are benzodiazepines and other hypnotics, which can act within 10 minutes. The

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New Class Of Anti-inflammatory Drugs Developed -- ScienceDaily

Details: Scientists have discovered a new class of anti-inflammatory drugs. The new substances promise to be more effective and to cause fewer side effects than aspirin. In the treatment of pain

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Osteoporosis drugs compared for side effects, efficacy

Details: A study comparing the efficacy and tolerability of two popular osteoporosis drugs, denosumab and zoledronic acid, found that denosumab had a significantly greater effect on increasing spine bone

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Phosphorus-lowering Drugs Linked To Lower Mortality In

Details: The drugs, called phosphorus binders, were associated with improved survival in new dialysis patients, including those patients with only modest or even no increase in their blood phosphorus levels.

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