Trimethoprim Drug

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Trimethoprim C14H18N4O3 - PubChem

Details: Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid.The antibacterial activity of this agent is potentiated by sulfonamides. trimethoprim side effects in elderly

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Trimethoprim Uses, Side Effects & Warnings - Drugs.com

Details: Other drugs may affect trimethoprim, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using. Trimethoprim drug interactions (more … trimethoprim antibiotic

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Trimethoprim Oral: Uses, Side Effects, Interactions

Details: Trimethoprim is an antibiotic used to treat bacterial infections.It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections sulfamethoxazole trimethoprim medication

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Trimethoprim: Uses, Interactions, Mechanism of Action

Details: Approximately 10-20% of an ingested trimethoprim dose is metabolized, primarily in the liver, while a large portion of the remainder is excreted unchanged in the urine. 14 Following oral administration, 50% to 60% of trimethoprim is excreted in the urine within 24 hours, approximately 80% of which is unchanged parent drug. 13. Half-life trimethoprim warnings

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Trimethoprim (Trimethoprim Tablet): Uses, Dosage, Side

Details: Trimethoprim is a prescription medicine used to treat the symptoms of bacterial infections. Trimethoprim may be used alone or with other medications. Trimethoprim belongs to a class of drugs called Antibiotics, Other. It is not known if Trimethoprim is safe and effective in children younger than 12 years of age. trimethoprim precautions

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Trimethoprim (Trimpex) - Side Effects, Interactions, Uses

Details: Trimethoprim is an antibiotic that is used to treat bladder or kidney infections, or ear infections caused by certain bacteria. Trimethoprim may also be used for purposes not listed in this trimethoprim long term use

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Trimethoprim Tablets - Drugs.com

Details: Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 11 Oct 2021), Cerner Multum™ (updated 1 Oct 2021), … trimethoprim antibiotic class

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Sulfamethoxazole And Trimethoprim (Oral Route) Description

Details: Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms:

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Trimethoprim (trimethoprim) dose, indications, adverse

Details: Trimethoprim use is contraindicated in folate deficiency megaloblastic anemia. Trimethoprim interferes with folate metabolism and should be used with caution in patients with folate deficiency. Patients should be aware of signs of hematologic disorders and, if necessary, have a complete blood count taken. If blood dyscrasias occur, the drug

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Trimethoprim: Generic, Uses, Side Effects, Dosages

Details: Trimethoprim has moderate interactions with at least 124 different drugs. Trimethoprim has mild interactions with at least 29 different drugs. This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.

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Trimethoprim - an overview ScienceDirect Topics

Details: Trimethoprim is a dihydropyrimidine antimicrobial and antiparasitic agent. It is the prototype of a group of nonsulfonamide drugs that inhibit dihydrofolate reductase in bacterial and protozoal cells. Although introduced as an antimalarial agent, it is now used primarily as an antibacterial agent, especially in combination with sulfamethoxazole.

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Trimethoprim/sulfamethoxazole - Wikipedia

Details: The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis; this is where the sulfamethoxazole comes in, its role is in depleting the excess DHF by preventing it from being synthesised in the first place.

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Trimethoprim: Basics, Side Effects & Reviews

Details: Learn about trimethoprim, potential side effects, proper use and dosing, and popular alternatives. Read reviews from GoodRx users who have taken trimethoprim and find the latest news on the drug.

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trimethoprim oral Interactions with Other Medication

Details: Does TRIMETHOPRIM Interact with other Medications? Severe Interactions . These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for

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Trimethoprim - an overview ScienceDirect Topics

Details: In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Rosiglitazone. Trimethoprim is a selective inhibitor of CYP2C8 in vitro. Rosiglitazone is predominantly metabolized in the liver by CYP2C8. The effect of trimethoprim on rosiglitazone metabolism in vitro has been determined in pooled liver microsomes and in a randomized crossover study in eight healthy subjects, who took a single

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Sulfamethoxazole/Trimethoprim VCA Animal Hospital

Details: Amoxicillin-clavulanic acid, also known as amoxicillin and clavulanate potassium, is a synthetic penicillin-type antibiotic used to treat infections caused by gram-positive and gram-negative bacteria. It is used to treat skin and soft tissue infections, and periodontal disease. Amoxicillin-clavulanic acid comes in tablet form, or may be

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Primsol (trimethoprim): UTI Antibiotic Side Effects & Dosage

Details: Primsol (trimethoprim) is a drug prescribed for the treatment of uncomplicated urinary tract infections. Side effects include diarrhea, abdominal pain, abnormal taste, swelling of the tongue. Drug interactions, warnings and precautions, and pregnancy and breastfeeding safety information should be reviewed prior to taking any medication.

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Trimethoprim (Primsol) Davis’s Drug Guide

Details: Download the Davis's Drug Guide app by Unbound Medicine. 2. Select Try/Buy and follow instructions to begin your free 30-day trial. You can cancel anytime within the 30-day trial, or continue using Davis's Drug Guide to begin a 1-year subscription ($39.95) trimethoprim. General.

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Trimethoprim Drug Information - Indications, Dosage, Side

Details: Generic Name : Trimethoprim Pronunciation : try-METH-oh-prim Latest prescription information about Trimethoprim. Learn how to pronounce the drug's

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Postcoital antimicrobial prophylaxis for recurrent urinary

Details: Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use* Urethra / microbiology Urinary Tract Infections / prevention & control* Vagina / microbiology Substances Trimethoprim, Sulfamethoxazole Drug Combination

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Acute kidney injury associated with trimethoprim

Details: Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage* Trimethoprim, Sulfamethoxazole Drug Combination / adverse effects* Urea / blood Substances Anti-Bacterial Agents Trimethoprim, Sulfamethoxazole Drug Combination Urea

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Trimethoprim-Sulfamethoxazole - Drugs and Lactation

Details: With healthy, fullterm infants it appears acceptable to use sulfamethoxazole and trimethoprim during breastfeeding after the newborn period. The time of greatest risk for hemolysis in fullterm newborns without glucose-6-phosphate dehydrogenase (G6PD) deficiency might be as short as 8 days after birth.[1] Until further data are accumulated, alternate agents should probably be used in …

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Trimethoprim - Drugs and Lactation Database (LactMed

Details: Drug Levels. Maternal Levels. In 20 mothers in the immediate postpartum period given oral trimethoprim, peak milk levels occurred 3 hours after the dose.

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Morbilliform drug eruptions caused by trimethoprim

Details: Description. Trimethoprim–sulfamethoxazole is a commonly prescribed antibiotic, mainly used in the treatment of urinary tract infection. Other indications included treatment of infections, such as Pneumocystis jiroveci, Toxoplasma gondii, Stenotrophomonas maltophilia and community-associated methicillin-resistant Staphylococcus aureus.Although this drug is well tolerated, it often causes

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sulfamethoxazole 800 mg-trimethoprim 160 mg tablet

Details: Brand name (s) Bactrim , Septra. Uses. This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).

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Drug Monograph: Trimethoprim Sulfamethoxazole (Bactrim

Details: In humans, trimethoprim and sulfamethoxazole were detected in the fetal placenta, umbilical cord blood, amniotic fluid and fetal tissues (liver, lung), indicating placental transfer of both drugs. Metabolism : Approximately 50 - 70% of the trimethoprim dose and 10 - 30% are excreted unchanged.

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BACTRIM™ - Food and Drug Administration

Details: To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sul-famethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

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Trimethoprim/sulfamethoxazole (Bactrim, Septra - Drug

Details: Davis’s Drug Guide for Nurses App + Web from F.A. Davis and Unbound Medicine covers 5000+ trade name and generic drugs. Includes App for iPhone, iPad, and Android smartphone + tablet. Handbook covers dosage, side effects, interactions, uses.

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Sulfamethoxazole and trimethoprim C24H29N7O6S - PubChem

Details: Sulfamethoxazole with trimethoprim is a fixed antibiotic combination that is widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections. Like other sulfonamide-containing medications, this combination has been linked to …

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TRIMETHOPRIM Drug BNF content published by NICE

Details: Trimethoprim can be given as a single dose for the prophylaxis of recurrent urinary-tract infection following exposure to a trigger, but this dosing regimen is not licensed. Not licensed for treatment of pneumocystis pneumonia.

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Package leaflet: Information for the patient Trimethoprim

Details: Trimethoprim tablets 3 How to take Trimethoprim tablets 4 Possible side effects 5 How to store Trimethoprim tablets 6 Contents of the pack and other information 1 What Trimethoprim tablets are and what they are used for Trimethoprim Tablets belong to a group of medicines known as antibacterials.

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Trimethoprim and Potassium-Sparing Drugs: A Risk for

Details: Trimethoprim-Induced Hyperkalemia Trimethoprim (TMP)—sulfamethoxazole (eg, Bactrim, Septra) is a commonly used antibiotic combination. Its best known potential drug interactions involve the ability of sulfamethoxazole to inhibit the metabolism of cytochrome P450 2C9 substrates, such as warfarin or oral hypoglycemic agents.

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polymyxin B sulfate/trimethoprim - Drug Summary - PDR.Net

Details: Polymyxin B Sulfate, Trimethoprim Sulfate/Polymyxin B, Trimethoprim/Polytrim Ophthalmic Sol: 1mL, 10000-1mg DOSAGE & INDICATIONS For the treatment of ocular infections, including bacterial conjunctivitis and blepharoconjunctivitis, caused by susceptible strains of bacteria.

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Delirium Associations with Antibiotics: A

Details: Drug Administration (FDA) [25]. FAERS data contain drug information (drug name, active ingredient, route of admin-istration, the drug’s reported role in the event) and reac-tion information. Healthcare professionals, consumers or manufacturers may submit reports. The types of data found in FAERS include reason for administration, specic reac-

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sulfamethoxazole/trimethoprim Drug Interactions

Details: amantadine. sulfamethoxazole/ trimethoprim (generic) +. amantadine. 1 interaction. Avoid/Use Alternative. trimethoprim + amantadine. avoid combo: combo may incr. amantadine levels, risk of psychosis, other adverse effects (mechanism unknown; renal excretion possibly decreased) amiloride.

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DailyMed - SULFAMETHOXAZOLE AND TRIMETHOPRIM tablet

Details: The trimethoprim component of sulfamethoxazole and trimethoprim may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors.

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Sulfamethoxazole / Trimethoprim - Suspension NIH

Details: The trimethoprim component of sulfamethoxazole and trimethoprim oral suspension may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors.

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Sulfamethoxazole: Uses, Interactions, Mechanism of Action

Details: Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. 9 It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of

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